Histology Flashcards

1
Q

Can you name of cells of the pulp?

A
  • Odontoblasts
  • Fibroblasts
  • Undifferentiate mesenchymal cells
  • Inflammatory cells (lymphocytes & macrophages) also (plasma cells & mast cells)
  • Intercellular matrix
  • Connective tissue
  • Collagen = Type I, III, IV
  • Vascular tissues
  • Neural tissues
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2
Q

Can you name the five layer starting from the Dentin to the Pulp Proper?

A
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3
Q

What do undifferentiated mesenchymal cells do?

A

Replace irreversibly damage odontoclasts

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4
Q

What germ layer does the pulp originate from?

A

Pulp derived from cephalic neural crest - neural crest cells arise from ectoderm

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5
Q

What is the first type of Dentin Formed?

A

Mantle Dentin

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6
Q

What is development dentin?

A

Formed during tooth development

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7
Q

What is Circumpulpal Dentin?

A
  • Major part of development dentin
  • Intertubular dentin
  • Peritubular dentin
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8
Q

Is Predentin mineralized or unmineralized?

A

Unmineralized Dentin

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9
Q

What is Secondary Dentin?

A

Physiologically formed after root development is complete

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10
Q

How does Tertiary Dentin form?

A

Response to irritation

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11
Q

Under the umbrella of Tertiary Dentin, you have reactionary and reparative dentin - how do they differ?

A
  • Reactionary: Produced by original odontoblasts
  • REparative: Produced by recruited underrentiated mesenchymal cells as the original odontoblasts have been destroyed
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12
Q

How many dentinal tubules are present at the DEJ/CEJ relative to the Pulpal Wall?

A
  • DEJ.CEJ = 10,000 - 25,000 per sq mm
  • Pulpal Wall = 30,000 - 52,000 per sq mm
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13
Q

What is the diamter of dentin tubles at the DEJ/CEJ relative to the Pulpal Wall?

A
  • Diameter at DEJ/CEJ = 1 - 2 microns
  • Diamaeter at Pulpal Wall = 3 - 4 microns

*Bacteria < 1 nm in diamter

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14
Q

What is the brakdown of dentin?

A
  • 45% inorganic - hydroxyapatite crystals
  • 33% organic - collagen and ground tissue
  • 22% dentinal fluid
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15
Q

Can you describe the Hydrodynamic Theory?

A
  • Exposed dentinal tubules
  • Rapid fluid movement…in—out
  • Caused by heat, cold, air, probing, hyper-osmotic solution
  • A-delta fibers stimulated
  • Result - dentinal hypersensitivity

*Inward flow of heat - outward flow - cold, air blasts; produces stronger nerve response

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16
Q

What are some examples of Afferent Sensory fibers of the pulp?

A
  • A Delta
  • A Beta
  • C Fibers
17
Q

What is an example of a an Efferent sensory fiber of the pulp?

A
  • C: sympathetic fibers - vasoconstriction
  • No proprioceptive fibers
18
Q

Describe A Delta Fibers?

A
  • Large
  • Myelinated
  • Quick
  • Sharp
  • Shooting pain
  • Full formed 3 - 5 years post eruption
19
Q

Describe A beta fibers…

A
  • Myelinated, but few in #
20
Q

Describe Afferent C fibers…

A
  • Small
  • Unmyelinated
  • Delayed
  • Dull
  • Aching
  • Burning Sensation
21
Q

Describe the circulatory system of the pulp…

A
  • Arterioles, capillaries, vanules
  • A-V anastomoses
  • Lymphatics
  • Unyielding denin walls
  • Irreversible Damage
  • Poor collateral circulation
  • Degenerative inflammation
  • Lymphatics abosr the larger molecules that canno be absorbed by the capillaries
22
Q

How close does a carious lesion need to be to elicit a significant increase in the extent of the inflammation?

A

0.5 mm

23
Q

What cells make up the “chronic” reponse to pulpal inflammation?

A

Lymphocytes and Macrophages

24
Q

Describe the pulpal response to caries…

A
  1. Inflammatory reaction preceds bacteria
  2. Chronic response: lymphocytes/macrophages
  3. “Acute response” 0.5 mm
  4. Edem - localized
  5. Microabscess
  6. Pressure - loalized
  7. Degeneration
  8. Pulp becomes necrotic when # of bacteria out number inflammatory response
25
Q

What is the change in microbes from healthy to pathogenic?

A

Aerobic to Anaerobic (facultative anaerobes (can grow with or without oxygen) to obligate anaerobes (which cannot use oxygen for growth and can even be harmed by it)

26
Q

What causes periapical pathosis?

A

Bacteria