Anesthesia Flashcards
If the pKa is lower, this equals faster or slower onset time?
Faster!
What is pKa?
The pKa of the anestehtic is the pH at which the anesthetic exists in 50% acid and 50% base.
Sofor lidoaine, with a pKa of 7.9, at a normal tissue pH of 7.4, is 25% base.
In an inflammatory situation where the tissue pH can be much lower, the acidity results in lidocaine existing in the base form 1%. This could make one wonder how a local anestehtic could work at all when inflammation was present.
Where are Amides hydrolized?
Liver
Where are Esters Hydrolized?
Plasma
What types of issues can be associated with Septoacaine and Mandiblar IA blocks?
Paresthesia
What are some examples of nerve blocks?
- Traditional IA
- Gow Gates
- Akinosi
What are some supplemental local anesthetic techniques?
- Infiltration
- Intraligmentary
- Intraosseous
- Intrapulpal
How does Stabident work?
