Histology Flashcards

1
Q

locations of 5 alpha reductase

A

sebaceous glands
hair follicles
prostate

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2
Q

does the development of the testis require hormone?

A

no. It only requires transcription factors

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3
Q

lymphatic drainage of the scrotum

A

inguinal lymph nodes

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4
Q

lymphatic drainage of the testis

A

para-aortic lymph nodes

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5
Q

What do the magnocellular neurons produce?

A

oxytocin & ADH

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6
Q

transcription factor required for synthesis of collagen and testicular development

A

Sox9

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7
Q

first hormone produced by the testis

A

AMH by the Sertoli cells

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8
Q

when does masculinization of the external genitalia have to occur?

A

12th week of gestation

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9
Q

comprises the blood-testis barrier

A

gap junctions between Sertoli cells & basement membrane

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10
Q

alpha1 receptor antagonist used for BPH to improve urine flow

A

tamsulosin

Adverse: retrograde ejaculation from relaxation of internal sphincter

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11
Q

provides 60% of volume of ejaculate

A

seminal vesicle

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12
Q

provides 40% of ejaculate

A

prostate & vas deferens

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13
Q

What is the major source of fructose and prostaglandins in semen?

A

seminal vesicle

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14
Q

Analogous to Cowper’s gland in male

A

Bartholin gland

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15
Q

Is the uterus intraperitoneal?

A

yes

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16
Q

is the ovary intraperitoneal

A

no, secondarily extraperitoneal

17
Q

What kind of epithelium covers the ovary?

A

germinal epithelium

source of ovarian cancer because of rupture and repair cycle

18
Q

In oocyte development what signals the presence of FSH receptors?

A

the appearance of the antrum. Prior to this the follicular development is independent of hormonal influence.

19
Q

What cells secrete VEGF and promote vascularization of the ovary?

A

granulosa cells

20
Q

When does the first polar body appear?

A

LH surge

21
Q

When does the second polar body appear?

A

fertilization

22
Q

what causes meiotic arrest?

A

c-kit

23
Q

What causes the LH surge?

A

sustained release of GnRH stimulated by NCY neurons

24
Q

important in branching of breast tissue

A

PTHrP

25
Q

inhibits lactation in pregnancy

A

placental estrogen & progesterone

26
Q

stimulates breast alveolar development

A

progesterone

27
Q

promotes ductal breast development

A

estrogen

28
Q

What is missing in breast cancer?

A

myoepithelium