Histology Flashcards
locations of 5 alpha reductase
sebaceous glands
hair follicles
prostate
does the development of the testis require hormone?
no. It only requires transcription factors
lymphatic drainage of the scrotum
inguinal lymph nodes
lymphatic drainage of the testis
para-aortic lymph nodes
What do the magnocellular neurons produce?
oxytocin & ADH
transcription factor required for synthesis of collagen and testicular development
Sox9
first hormone produced by the testis
AMH by the Sertoli cells
when does masculinization of the external genitalia have to occur?
12th week of gestation
comprises the blood-testis barrier
gap junctions between Sertoli cells & basement membrane
alpha1 receptor antagonist used for BPH to improve urine flow
tamsulosin
Adverse: retrograde ejaculation from relaxation of internal sphincter
provides 60% of volume of ejaculate
seminal vesicle
provides 40% of ejaculate
prostate & vas deferens
What is the major source of fructose and prostaglandins in semen?
seminal vesicle
Analogous to Cowper’s gland in male
Bartholin gland
Is the uterus intraperitoneal?
yes
is the ovary intraperitoneal
no, secondarily extraperitoneal
What kind of epithelium covers the ovary?
germinal epithelium
source of ovarian cancer because of rupture and repair cycle
In oocyte development what signals the presence of FSH receptors?
the appearance of the antrum. Prior to this the follicular development is independent of hormonal influence.
What cells secrete VEGF and promote vascularization of the ovary?
granulosa cells
When does the first polar body appear?
LH surge
When does the second polar body appear?
fertilization
what causes meiotic arrest?
c-kit
What causes the LH surge?
sustained release of GnRH stimulated by NCY neurons
important in branching of breast tissue
PTHrP
