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This one has histology pictures > histo gynae > Flashcards

histo gynae Flashcards

1
Q
A
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2
Q

PID definition

A

acending infection from vagina and cervix to uterus and tubes resulting in inflammations and adhesions

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3
Q

complications of PID

A

ectopic pregnancy ectopic pregnanc tubo-ovarian abscess plical fusion peritonits Fits-High-Curtis syndrome

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4
Q

Fitz Hugh Curtis syndrome symptoms and signs

A

RUQ pain perihepatitis violing string peri-hepatic adhesion

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5
Q

three theories of endometriosis aetiology

A
  1. retrograde menstruation 2. metaplastic transformation of coelomic cells 3. lyphatic/ vascular dissemination of endometrial tissue
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6
Q

symptoms of endometriosis

A

dyspareunia pelvic pain dysmennorhea cyclical PR/ umbilbial bleeding fixed retroverted uterus nodules in vagina/ fornix

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7
Q

macroscopic signs of endometriosis

A

red-blue to brown nodules “powder burns” chocolate cysts

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8
Q

microscopic signs of endomedtriosis

A

endometrial glands and stroma

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9
Q

adenomyosis definition

A

ectopic endometrial tissue deep within myometrium

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10
Q

adenomyosis symptoms

A

deep dyspareunia HMB dysmenorrhea

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11
Q

signs ofadenomyosis

A

globular uterus

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12
Q

definition of leiomyoma

A

benign tumour of smooth muscle origin in femal genital tract

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13
Q

symptoms of leiomyoma

A

HMB dysmenorrhea pressure effects e.g. urinary frequency

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14
Q

complication of leiomyoma

A

post partum torsion red degeneration in pregnancy transformation to leiomyosarcoma

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15
Q

what causeses leiomyoma to grow

A

oestrogen therefore grows in pregnancy and shriks in menopause

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16
Q

PMB is what until proved otherwise

A

endometrial carcinoma

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17
Q

risk factors for endometrial carcinoma

A

nullioparity early menarche, late menopause tamoxifen

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18
Q

what type of tumour is in endometrial cancer

A

adenocarcinoma although may have some squasmous differentiation

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19
Q

how is endometrial cancer staged

A

FIGO

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20
Q

what is pagets disease of the vulva

A

adenocarcinoma in situ

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21
Q

what is VIN associated with

A

HPV16

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22
Q

what is usual type of VIN

A

warty/ basaloid/ mixed

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23
Q

differnetiated type of VIN

A

more likely to progress to SCC

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24
Q

subtypes of epithelial ovarian cancer

A

serous cystadenoma mucinous cystadenoma endometroid clear cell

25
Q

serous cystadenoma cell type

A

columnar epithelium

26
Q

microscopic findings o n serous cystadenoma ovarian cancer

A

psammoma bodies

27
Q

what cell types are involved in mucinous cystadenoma in ovarian cancer

A

mucinous secreting cellls

28
Q

what is psueudomyxoma peritonei

A

metatastatic spread of mucinou cystadenoma from the apendix

29
Q

what do mucinous cystadenoma (ovarain ca) produce

A

oestrogen

30
Q

what cell type is involved in endometroid ocvarian cancer

A

endometrium mimicks tubular cells

31
Q

what are the microscopic findings in cleazr cell ovarian cancer

A

intracellular glycogen abundant cytoplasm hobnail appearance

32
Q

what is the prognosis in clear cell ovarian cancer

A

poor

33
Q

dysgerminoma (female)

A

female equivalent of testicular seminom

34
Q

how are dysgerminomas treated

A

radiotherapy

35
Q

are dysgerminomas benign or malignant

A

benign in adults malignant in children

36
Q

teratomas secrete what (gynae)

A

AFP

37
Q

what is the other name for a mature teratoma

A

dermoid cyst

38
Q

what do choriocarcinomas usually secrete

A

HCG MALIGNANT

39
Q

location of teratoma

A

bilateral

40
Q

what condition is fibroma associated with (ovarian)

A

Meig’s syndrome

41
Q

what is Meig’s syndrome

A

ovarian fibroma +ascites+ pleural effusion

42
Q

what the the three subtypes of sex cord tumours

A

fibroma granulosa-theca cell tumour sertoli-leydig cell tumour

43
Q

what do granulosa-theca cell tumours produce

A

oestrogen

44
Q

what do sertoli leydig cell tumours produce

A

androgens

45
Q

what are symptoms of granulosa-theca cell tumours

A

irregular periods, breat enlargment

46
Q

what are symptoms of sertoli-leydig cell tumours

A

virilisation enlarged clitoris deep voice breast atrophy

47
Q

what does the squamocolumnar junction separate (gynae)

A

the endocervical columnar glandular epithelium the outer cervix has squamous epithelium

48
Q

what happens at the tranformation zone

A

squamous metaplasia columnar epithelium transforms to squamous epithelium

49
Q

what are RF for CIN

A

HPV 16 and 18 early first interxourse multiple partners smoking immunosuppression

50
Q

histological grades for CIN

A

CIN1,2,3,

51
Q

cytological grades for CIN

A

mild, moderate or severe dyskaryosis

52
Q

what is CGIN

A

cervical glandular intraepithlial neoplasia

53
Q

how to treat CGIN

A

excise entire endocervix

54
Q

cervical carcinoma tumour types

A

SCC adenocarcinoma

55
Q

cervical cancer sx

A

IMB PCB PMB discharge pain

56
Q

change from CIN to cervical ca

A

invasion o f BM

57
Q

how to stage cervical ca

A

FIGO

58
Q
A

This one has histology pictures (5 decks)

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