HISTO: Fundamentals of Histology Flashcards
Where would you see these in acute appendicitis?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/787/q_image_thumb.png?1627404385)
Neutrophils mean acute inflammation
Would be seen in the crypts in acute appendicitis (as below). Also in gastritis and mastitis.
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/787/a_image_thumb.png?1627405120)
What are these cells and what are they associated with?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/789/q_image_thumb.png?1627405225)
Lymphocytes and plasma cells - chronic inflammation and lymphomas. More plasma usually means lymphocytes // less is a plasma cell.
What cells can be seen in this picture?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/790/q_image_thumb.png?1627405338)
This is a picture of a crypt in colitis. The outside of the circular structure is mainly lymphocytes whereas the inside is neutrophils (recognised by the irregular nuceli). This signifies acute on chronic inflammation.
What is seen in this slide of sheets of lymphocytes?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/791/q_image_thumb.png?1627405441)
Lymphoma
What is this cell? What are they associated with?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/797/q_image_thumb.png?1627405467)
Eosinophil - bi-lobed nucleus and red granules.
Allergic reactions, parasitic infections (e.g. schistosomiasis), tumours e.g. Hodgkin’s disease.
What is this?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/799/q_image_thumb.png?1627405623)
Oesophagus with feline contractions. Due to eosinophil infiltration from an allergic reaction.
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/799/a_image_thumb.png?1627405677)
Where are these cells commonly found?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/802/q_image_thumb.png?1627405731)
In urticarial reactions e.g. skin. If you look at the biopsy of the skin then you will find these.
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/802/a_image_thumb.png?1627405776)
What is this cell and what is it associated with?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/805/q_image_thumb.png?1627405836)
Macrophages - associated with late acute inflammation (clean up after an infection), chronic inflammation (including granulomas*). They are also found in the alveoli.
*granulomas - macrophage groups
What are these and which infection are they associated with?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/808/q_image_thumb.png?1627406075)
Shown are sheets of epithelioid macrophages and some Langerhan’s cells (giant). They are found in TB as below in caseous lesions in the lung shown.
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/808/a_image_thumb.png?1627406043)
What stain is shown?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/813/q_image_thumb.png?1627406195)
Ziehl-Neelson stain for TB - phospholipid in the bacteria binds the red dye in the stain giving this colour.
Ontological classification - classified based on the cells that we think they came from.
What is a carcinoma?
Tumour of epithelial cells - most common seen in practice
Name 3 types of carcinomas.
- Squamous cell carcinoms
- Adenocarcinomas
- Transitional cell carcinomas
What is shown here?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/820/q_image_thumb.png?1627406538)
Intercellular bridges in squamous cells.
Below is the zoomed out version shows keratin production which would be seen in a tumour.
![](https://s3.amazonaws.com/brainscape-prod/system/cm/385/829/820/a_image_thumb.png?1627406569)
How can you recognise squamous cell carcinomas?(2)
Keratin production and intercellular bridges