Histamines Flashcards
Also known as biogenic amines
Biologically active amines
Examples of Biologically active amines
Histamine
Seretonin
Derived from metabolism of 20-carbon unsaturated fatty acids
Lipid Derived (Eicosanoids)
Peptides that can constrict or dilate blood vessels
Vasoactive Polypeptides
Examples of Eicosanoids
Prostaglandins
Leukotrienes
Thromboxanes
Examples of vasoactive polypeptides
Kinins
Angiotensin
Endothelin
Process that turns histidine to histamine
Decarboxylation
Sites of Biosynthesis of Histamine (4)
Mast Cells
Basophils
Stomach
CNS
Also known as Local Hormones
Autocoids
Autocoids are not formed in the center of action (T/F)
FALSE (AT THE CENTER OF ACTION)
Enzyme that catalyzes Histidine to Histamine
L-histidine decarboxylase