Anxiolytic Drugs 1

Question 1

The MOST widely used anxiolytic drugs.

Answer 1

BENZODIAZEPINES

Question 2

______________ have largely replaced barbiturates and meprobamate in the treatment of anxiety,

Answer 2

BENZODIAZEPINES

Question 3

Mechanism of Action of Benzodiazepines

Answer 3

Bind to GABAA receptor subunits
at CNS neuronal synapse.

Question 4

Benzodiazepines DECREAESE frequency of chloride
channel opening enhancing membrane hyperpolarization (T/F)

Answer 4

False (INCREASE)

Question 5

Examples of Short Acting Benzodiazepines (2-8 hrs)

Answer 5

Oxazepam (Serax)
Triazolam (Halcion)
Clonazepam (Klonopin, Rivotril)
Midazolam (Versed, Dormicum)
Temazepam (Restoril)

Question 6

Short Acting Benzodiazepine are used as anxiolytics Except ______

Answer 6

Clonazepam - anticonvulsant

Question 7

Examples of Intermediate acting benzodiazepines (10-20 hrs)

Answer 7

Lorazepam (Ativan)
Alprazolam (Xanax, Xanor)
Temazepam (Restoril)
Flunitrazepam (Rohypnol)

Question 8

Examples of long acting benzodiazepines (1-3 days)

Answer 8

Diazepam (Valium, Anxionil)
Flurazepam (Dalmane)
Chlordiazepoxide (Librium)