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TERAPÉUTICA > HIPOLIPEMIANTES > Flashcards

HIPOLIPEMIANTES Flashcards

1
Q

en que horario tomar estatinas

A

en la noche

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2
Q

Cuando están contra indicadas las estatinas?

A

en el embarazo

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3
Q

Estatina + fibrato

A

aumenta riesgo de toxicidad muscular

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4
Q

estatina + macrólidos

A

aumenta riesgo de toxicidad muscular

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5
Q

Secuestradores de ácidos biliares

A

indicados para hipercolesterolemia
dosis separadas entre medicamentos cada 3h

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6
Q

contraindicación absoluta de secuestradores de ácidos biliares

A

> 400 mg/dL triglicéridos

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7
Q

SECUESTRADOR DE ÁCIDOS BILIARES

A

Colestiramina

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8
Q

FIBRATOS

A

Hipolipemiantes que disminuyen los triglicéridos
elevan HDL
2d ELECCIÓN en caso de fracaso con estatinas

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9
Q

FIBRATOS mecanismo

A

Agonistas de PPAR-alfa

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10
Q

FIBRATOS Medicamentos

A

Gemfibrozilo
Fenzofibrato
Bezafibrato

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11
Q

Gemfibrozilo dosis

A

900-1,200 mg al día

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12
Q

Fenzofibrato dosis

A

200mg/día

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13
Q

Bezafibrato dosis

A

400mg/ día

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14
Q

Ácido nicotínico

A

Disminuye triglicéridos pero requiere dosis altas

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15
Q

ácido nicotínico efecto secundario

A

vasofdilatación cutánea secundaria a liberación de prostaglandinas

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16
Q

contraindicación de ácido nicotínico

A

enfermedad hepática
úlcera péptica

17
Q

EZETIMIBE

A

Disminuye absorción intestinal de colesterol y estériles, disminuye formación de quilomicrones

TERAPÉUTICA (4 decks)

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