Higher!! Flashcards

1
Q

Cellular differentiation?

A

Process of cells that have a specific gene to make specific protein.

Allows cell to carry out specialised tasks

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2
Q

Embryonic stem cells?

A

Cells in embyo that can differentiate into all cells, pluripotent

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3
Q

Tissue stem cells?

A

Involved in growth repair and replacement of dead cells, multipotent

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4
Q

Pluripotent?

A

Differentiate into all cell types

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5
Q

Multipotent?

A

Can only differentiate (turn into) cells from that tissue

Eg: bone marrow makes RBC

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6
Q

Stomatic cells?

A

Any cell that isn’t involved with reproduction

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7
Q

Gremlins cells?

A

Gametes (sex cells) + the stem cells that divide to form gametes

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8
Q

Cancer?

A

Cells that divide too much

Which = too many cells called tumour

Spreads through the whole body can make secondary tumours

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9
Q

Tumour?

A

A mass of abnormal cells

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10
Q

Therapeutic use of stem cells?

A

Repair of damaged or sick organs or tissue

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11
Q

Research use of stem cells?
Embryo

A

Stem cells being used as model cells to study how sicknesses are formed or being used for drug testing

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12
Q

What is an RNA polymerase and what does it do?

A

It’s an enzyme and it adds Complementary nucleotides to mRNA strand

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13
Q

What is a primary mRNA strand?

A

Strands by mRNA that are made from introns and exons

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14
Q

What is exon?

A

Coding area of mrna

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15
Q

What is intron?

A

Non coding area of mrna

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16
Q

What is mature mRNA strand?

A

Strand with only exons

17
Q

Types of gene mutations?

A

Substitution
-nonsense
-missense
-spicing site

Deletion

Insertion

18
Q

Types of gene mutations?

A

Substitution
-nonsense
-missense
-spicing site

Deletion

Insertion

19
Q

What is a missense mutation?

A

A substitution type of mutation

One amino acid being changed for another

Results in little effect on protein

20
Q

What is nonsenese?

A

A substitution type of mutation

Amino acid codon being replaced by a stop codon

Makes protein shorter

21
Q

What is nonsenese?

A

A substitution type of mutation

Amino acid codon being replaced by a stop codon

Makes protein shorter

22
Q

What is splice site?

A

Substitution type of mutation

Might result in soke introns staying and exons leaving in the mature transcript

23
Q

What is splice site?

A

Substitution type of mutation

Might result in soke introns staying and exons leaving in the mature transcript

24
Q

Deletion and insertion are?

A

Frame shift effects not mutation since they make the structure different then before

25
Chromosome mutations? Lethal
Deletion Duplication Translocation Inversion
26
What is deletion (Chromosomes)
When a section of chromosome is removed
27
Duplication? (Chromosome)
When a part of chromosome is adding from its homologous partner
28
Translocation? (Chromosome)
Section of chromosome is added to another chromosome but its not its homologous partner
29
Inversion? Chromosome
When a section of chromosome is reversed
30
What is bioformatics?
The uses of computers that analyse genetic data to compare sequences of dna. important in genome research keeps a record of all dna produced Interprets info of dna data
31
Why is personalised medicine used?
Because Illnesses an involve genes from parents and or from the environment Examples Genetic - BRCA1 , BRCA2 high chance of heart cancer. Parent -APCE-e4- increase risk of getting alzhemiers
32
Why have personal medication for everyone?
Everyone has different genetic makeup Different metabolism Same drugs have different effects on the body Can help lead to predictions of likely illness that might develop
33
Role of rna polymerase enzyme?
creating a complementary strand of nucleic acid, called RNA, from a single-stranded DNA template