Hi-Yield Flashcards
Suppresses the appetite center
Decrease beta-oxidation of fatty acids for fuel
TNF-alpha
Irreversible catabolic reaction (wasting syndrome)
Increased in TNF-alpha
Cachexia
Distant effects of a tumor unrelated to metastasis
May involve ectopic secretion of hormone
Paraneoplastic Syndrome
State the underlying cancer for each syndrome:
- Lambert-Eaton Myasthenia
- Acanthosis nigricans
- Hypertrophic osteoarthropathy (clubbing)
- Trousseau Syndrome
- Non-bacterial thrombotic endocarditis
- Red Cell Aplasia
- Nephrotic Syndrome
- Lung carcinoma
- Visceral Malignancies
- Lung Ca
- Pancreatic Ca
- Colon Ca
- Thymoma
- Hodgkin’s Lymphoma / Lung Ca
Tumor marker for:
Prostate Cancer
PSA, Prostate Acid Phosphatase
Tumor marker for:
Colorectal and Pancreatic Cancer
Gastric Ca and Breast CA
CEA
Tumor marker for:
Hepatocellular CA
Non-seminomatous GCT (yolk sac)
AFP
Tumor marker for:
Hydatidiform mole
Choriocarcinoma
Gestational Trophoblastic Tumor
beta-HCG
Ovarian, Malignant Epithelial Tumors
CA-125
Tumor marker for:
Melanoma, Neural Tumors, Astrocytoma
S-100
Metastases to bone, Obstructive biliary disease, Paget Disease of the bone
Alkaline Phosphatase
Tumor marker for:
Neuroblastoma, Lung and Gastric CA
Bombesin
Tumor marker for:
Hairy Cell Leukemia (B-Cell Neoplasm)
TRAP
Pancreatic Adenocarcinoma
CA-19-9
Chemotherapy causes release of break-down products of dying cancer cells
Multiple electrolyte abnormalities: Hyperkalemia Hyperphosphatemia Hyperuricemia HYPOcalcemia
Tumor Lysis Syndrome