Endocrine Flashcards

0
Q

Drugs that can cause SIADH

A

Chlorpropamide
Clofibrate
Phenothiazine

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1
Q

Most common cause of SIADH

A

Small Cell Lung CA

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2
Q

Most common cause of hypopituitarism in children

A

Craniopharyngioma

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3
Q

Derived from Rathke’s pouch

WNT Signaling Pathway

A

Craniopharyngioma

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4
Q

2 types of Craniopharyngioma

A

Adamantinomatous
-Wet Keratin Lamellae

Papillary

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5
Q

Hypothyroidism that develops in children

A

Cretinism

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6
Q

aka Myxedema

A

Gull Disease

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7
Q

Hypothyoridism developing in the Older Child or Adult

A

Myxedema

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8
Q

CTL4 Polymorphisms
Anti-thyroglobulin
Anti-TPO
Hurthle Cells / Oxyphil / Oncocytic / Ashkenazi Cell

A

Hashimoto Thyroiditis

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9
Q

aka Granulomatous Thyroiditis
De Quervain Thyroiditis
Giant Cell Thyroiditis

A

Subacute Thyroiditis

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10
Q

Most common cause of painful thyroid gland

A

Subacute Thyroditis

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11
Q

Multinucleate Giant Cells

A

Subacute Thyroiditis

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12
Q

aka Painless Thyroiditis

Post-partum Thyroditis

A

Lymphocytic Thyroiditis

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13
Q

Psammoma Bodies

Orphan Annie

A

Papillary Thyroid Carcinoma

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14
Q

Hurthle Cell Carcinoma

A

Follicular Thyroid Carcinoma

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15
Q

Giant Cells
Spindle Cells
Mixed spindle and giant cells
Cytokeratin as marker

A

Anaplastic Thyroid Carcinoma

16
Q

Parafollicular Cells or C cells
Secrete Calcitonin
Amyloid

A

Meullary Thyroid Carcinoma

17
Q

Diseases that produce Amyloid

A
Medullary Thyroid Carcinoma
Multiple Myeloma
Alzheimer's Disease
Type 2 DM
Insulinoma
18
Q
Chief Cell Hyperplasia
Water-Clear Cell Hyperplasia
Osteitis Fibrosa Cystica
Nephrolithiasis
Nephrocalcinosis
A

Primary Hyperparathyroidism

19
Q

Most common cause of secondary hyperparathyroidism

A

Renal failure

20
Q

Water-Clear Cell
Metastatic Calcification
Renal Osteodystrophy
Calciphylaxis

A

Secondary Hyperparathyroidism

21
Q

Anti-GAD

Anti-ICA513

22
Q

Causes of Hypercalcemia?

A
CHIMPANZEES
Calcium Supplements
Hyperparathyroidism
Iatrogenic
Milk Alkali Syn
Paget Disease
Acromegaly
Neoplasia
Zollinger-Ellison Syn
Excess Vit D
Excess Vit A
Sarcoidosis
23
Q

Kimmelsteil-Wilson Nodules

Glomerulosclerosis

A

Diabetes Mellitus

24
Most common pancreatic neoplasm
Insulinoma
25
Giant Islet Cells Amyloid Deposits Nesidioblastosis
Insulinoma
26
Necrolytic Migratory Erythema
Glucagonoma
27
Crooke Hyaline Change
Cushing Syndrome
28
Most common causes of Hyperaldosteronism
``` Idiopathic Conn Syndrome (Adenoma) ```
29
Spironolactone bodies
Hyperaldosternism | Aldosterone-Producing Adenomas
30
aka Androgenital Syndromes Autosomal Recessive Salt wasting
Congenital Adrenal Hyperplasia
31
Most common enzyme deficiency in CAH
21-Hydroxylase Def
32
Waterhouse-Friderichsen Syndrome | Massive adrenal hemorrhage in fulminant Meningococcemia
Primary Acute Adrenocortical Insufficiency
33
aka Addison Disease
Primary Chronic Adrenocortical Insufficiency
34
Caused by a disorder in the hyopothalamus and pituitary affecting ACTH production Cortex may reduced to thin ribbon compozed of Zona Glomerulosa
Secondary Adrenocortical Insufficiency
35
Neoplasms composed of chromaffin cells which synthesize and release catecholamines and peptide hormones
Pheochromocytoma
36
ExtraAdrenal Pheochromocytoma
Paraganglioma
37
Zellballen | Salt and Pepper Chromatin
Pheochromocytoma
38
Dye that turns pheochromocytoma tumor a dark brown color (chromaffin)
Potassium Dichromate