HF Formulary Quiz

Question 1

Bisoprolol

Answer 1

Zebeta

Starting dose: 1.25 mg daily
Target dose: 10 mg daily

Adverse Effects:
- sinus bradycardia
- sinus arrest
- AV/SA node conductance disturbances
- reduced EF
- fatigue
- depression
- exercise intolerance
- withdrawal syndrome
- mask hypoglycemia events

Question 2

Bumetanide

Answer 2

Bumex

Starting dose: 0.5 - 1 mg QD/BID

Target Dose: 1-2 mg QD/BID

CrCl < 20-50 mL/min: 2 mg QD/BID

CrCl < 20 mL/min: 8-10 mg daily

Adverse Effects:
- hypotension
- hypokalemia
- hypomagnesemia
- hypocalcemia
- hyperuricemia
- otoxicity
- azotemia

Question 3

Candesartan

Answer 3

Atacand

Starting dose: 4 mg daily
Target dose: 32 mg daily

Adverse Effects:
- angioedema
- hypotension
- hyperkalemia
- AKI

Question 4

Carvedilol

Answer 4

Coreg, Coreg CR

Starting dose:
- 3.125 mg BID
- 10 mg daily

Target dose:
- 25-50 mg BID
- 80 mg daily

Adverse Effects:
- sinus bradycardia
- sinus arrest
- AV/SA node conductance disturbances
- reduced EF
- fatigue
- depression
- exercise intolerance
- withdrawal syndrome
- mask hypoglycemia events

Question 5

Chlorthalidone

Answer 5

Thalitone

Starting dose: 12.5-25 mg daily

Target dose: 50 mg daily

Adverse Effects:
- hypotension
- hypokalemia
- hypomagnesemia
- hypercalcemia
- hyperuricemia
- hyperlipidemia
- hyperglycemia
- sexual dysfunction
- azotemia

Question 6

Dapagliflozin

Answer 6

Farxiga

10 mg daily

Adverse Effects:
- hypotension
- volume depletion
- increased risk for UTI
- increased risk for genital infections
- DKA
- hypoglycemia

Question 7

Digoxin

Answer 7

Digitek, Lanoxin, Lanoxicaps

0.125-0.25 mg daily until 0.5-0.9 ng/mL serum concentration

Question 8

Empagliflozin

Answer 8

Jardiance

10 mg daily

Adverse Effects:
- hypotension
- volume depletion
- increase risk for UTI
- increase risk for genital infections
- DKA
- hypoglycemia

Question 9

Enalapril

Answer 9

Vasotec

Starting dose: 2.5-5 mg BID
Target dose: 10 mg BID

Adverse Effects:
- angioedema
- hyperkalemia
- AKI
- hypotension
- dry cough

Question 10

Fosinopril

Answer 10

Monopril

Starting dose: 5-10 mg daily
Target dose: 40 mg daily

Adverse Effects:
- angioedema
- hypotension
- hyperkalemia
- AKI
- dry cough

Question 11

Furosemide

Answer 11

Lasix

Starting dose: 20-40 mg QD/BID

Target dose: 20-160 mg QD/BID

CrCl < 20-50 mL/min: 160 mg QD/BID

CrCl < 20 mL/min: 400 mg daily

Adverse Effects:
- hypotension
- hypokalemia
- hypomagnesemia
- hypocalcemia
- hyperuricemia
- otoxicity
- azotemia

Question 12

Hydrochlorothiazide

Answer 12

Microzide, Esidrix, Hydrodiuril

Starting dose: 25 mg daily
Target dose: 100 mg daily

Adverse Effects:
- hypotension
- hypokalemia
- hypomagnesemia
- hypercalcemia
- hyperuricemia
- hyperlipedmia
- hyperglycemia
- sexual dysfunction
- azotemia

Question 13

Isosorbide Dinitrate/Hydralazine

Answer 13

Bidil

Starting dose: 20/37.5 mg TID
Target dose: 40/75 mg TID

Adverse Effects:
- headache
- flushing
- dizziness
- tachycardia
- lupus like syndrome
- fluid retention

Question 14

Lisinopril

Answer 14

Zestril, Prinivil

Starting dose: 2.5-5 mg daily
Target dose: 20-40 mg daily

Adverse Effects:
- angioedema
- hypotension
- hyperkalemia
- AKI
- dry cough

Question 15

Losartan

Answer 15

Cozaar

Starting dose: 25-50 mg daily
Target dose: 150 mg daily

Adverse Effects:
- angioedema
- hypotension
- hyperkalemia
- AKI

Question 16

Metoprolol Succinate

Answer 16

Toprol XL

Starting dose: 12.5-25 mg daily

Target dose: 200 mg daily

Adverse Effects:
- sinus bradycardia
- sinus arrest
- AV/SA node conductance disturbances
- reduced EF
- fatigue
- depression
- exercise intolerance
- withdrawal syndrome
- mask hypoglycemia events

Question 17

Omega-3-fatty acid

Answer 17

Lovaza, Omytrig, Vascepa

2-4 g QD/BID

Question 18

Quinapril

Answer 18

Accupril

Starting dose: 5-10 mg BID
Target dose: 20-40 mg BID

Adverse Effects:
- angioedema
- hypotension
- hyperkalemia
- AKI
- dry cough

Question 19

Potassium Chloride

Answer 19

Klor Con

Question 20

Ramipril

Answer 20

Altace

Starting dose: 1.25-2.5 mg daily
Target dose: 5 mg BID

Adverse Effects:
- angioedema
- hypotension
- hyperkalemia
- AKI
- dry cough

Question 21

Sacubitril/Valsartan

Answer 21

Entresto

24/26, 49/51, 97/103 mg BID

Adverse Effects:
- hypotension
- AKI
- angioedema
- hyperkalemia

Question 22

Spironolactone

Answer 22

Aldactone

CrCl 30-49 mL/min:
- starting dose: 12.5 mg daily or every other day
- target dose: 12.5-25 mg daily

CrCl > 50 mL/min:
- starting dose: 12.5-25 mg daily
- target dose: 25 mg daily

Adverse Effects:
- hyperkalemia
- hyponatremia
- gynecomastia
- impotence
- irregular menses

Question 23

Torsemide

Answer 23

Demedex

Starting dose: 10-20 mg daily

Target dose: 10-80 mg daily

CrCl < 20-50 mL/min: 40 mg daily

CrCl < 20 mL/min: 200 mg daily

Adverse Effects:
- hypotension
- hypokalemia
- hypomagnesemia
- hypocalcemia
- hyperuricemia
- otoxicity
- azotemia

Question 24

Valsartan

Answer 24

Diovan

Starting dose: 20-40 mg BID
Target dose: 160 mg BID

Adverse Effects:
- angioedema
- hypotension
- hyperkalemia
- AKI

Question 25

Captopril

Answer 25

Captovan, Captoril

Starting dose: 6.25-12.5 TID
Target dose: 50 mg TID

Adverse Effects:
- angioedema
- hypotension
- hyperkalemia
- AKI
- dry cough
- skin rash
- altered taste

Question 26

Eplerenone

Answer 26

Inspra

CrCl 30-49 mL/min:
- starting dose: 25 mg every other day
- target dose: 25 mg daily

CrCl > 50 mL/min:
- starting dose: 25 mg daily
- target dose: 50 mg daily

Adverse Effects:
- hyperkalemia
- hyponatremia

Question 27

Ivabradine

Answer 27

Corlanor

Starting dose: 2.5-5 mg BID
Target dose: 7.5 mg BID

Adverse Effects:
- fetal toxicity
- a-fib
- bradycardia
- AV/SA node conductance disturbances