CYP450 for Schizo, Insomnia, Anxiety, ADHD Flashcards

1
Q

Aripiprazole

A

CYP3A4 & CYP2D6 substrate

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2
Q

Brexipiprazole

A

CYP3A4 & CYP2D6 substrate

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3
Q

Cariprazine

A

CYP3A4 substrate

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4
Q

Asenapine

A

CYP1A2 & UGT substrate
- fluvoxamine

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5
Q

Clozapine

A

CYP1A2 substrate

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6
Q

Olanzapine

A

CYP1A2 substrate

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7
Q

Quetiapine

A

CYP3A4 substrate

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8
Q

Iloperidone

A

CYP2D6 substrate

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9
Q

Lurasidone

A

CYP3A4 substrate

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10
Q

Ziprasidone

A

CYP3A4 substrate (1/3) & aldehyde oxidase (2/3)

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11
Q

Risperidone

A

CYP2D6 substrate

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12
Q

Lumateperone

A

CYP3A4 substrate

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13
Q

Pimavanserin

A

CYP3A4 substrate

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14
Q

Valbenazine

A

CYP3A4 & CYP2D6 substrate

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15
Q

Deutetrabenazine

A

CYP2D6 substrate

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16
Q

Zolpidem

A

CYP3A4 substrate

17
Q

Zaleplon

A

CYP3A4 substrate

18
Q

Eszopiclone

A

CYP3A4 substrate

19
Q

Ramelteon

A

CYP1A2 substrate

20
Q

Tasimelteon

A

CYP1A2 substrate

21
Q

Suvorexant

A

CYP3A4 substrate

22
Q

Lemborexant

A

CYP3A4 substrate

23
Q

Daridorexant

A

CYP3A4 substrate

24
Q

Melatonin

A

CYP1A2 substrate

25
Q

Pitolisant

A

CYP3A4 & CYP2D6 substrate

CYP3A4 inducer

26
Q

Buspirone

A

CYP3A4 substrate

27
Q

Guanfacine ER

A

CYP3A4 substrate

28
Q

Atomoxetine

A

CYP2D6 substrate

29
Q

Viloxazine

A

CYP2D6 & UGT substrate

CYP1A2 inhibitor

30
Q

Bupropion

A

CYP2B6 substrate

CYP2D6 inhibitor