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PHRM 845 Dosing & Substrates > Formulary Quiz > Flashcards

Formulary Quiz Flashcards

1
Q

Amlodipine

A

Norvasc

5-10 mg daily

Side Effects:
- hypotension, facial flushing, dizziness, fatigue
- reflex tachycardia
- slight reduction in myocardial contractility
- peripheral edema

Monitoring:
- edema
- BP
- reflex tachycardia

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2
Q

Felodipine

A

Plendil

5-10 mg daily

Side Effects:
- hypotension, facial flushing, dizziness, fatigue
- reflex tachycardia
- slight reduction in myocardial contractility
- peripheral edema

Monitoring:
- edema
- BP
- reflex tachycardia

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3
Q

Nifedipine

A

CC: Adalat
XL: Procardia

30-60 mg daily

Side Effects:
- hypotension, facial flushing, dizziness, fatigue
- reflex tachycardia
- slight reduction in myocardial contractility
- peripheral edema

Monitoring:
- edema
- BP
- reflex tachycardia

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4
Q

Aspirin

A

Loading: 325 mg
Maintenance: 81 mg

Side Effects:
- GI bleeding
- hematologic (intracranial/extracranial hemorrhage)
- hypersensitivity

Monitoring:
- bleeding
- hypersensitivity
- take with food
- lifelong drug

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5
Q

Atenolol

A

Tenormin

Starting Dose: 25-50 mg daily

Target Dose: 100 mg daily

Side Effects: sinus bradycardia, sinus arrest, SA/AV node conductance disturbances, reduction in LVEF, fatigue, depression, exercise intolerance, mask hypoglycemia, withdrawal syndrome

Monitoring:
- HR (Rest: 50-60 bpm –> Exercise: < 100 bpm)
- BP

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6
Q

Bisoprolol

A

Zebeta

Maintenance Dose: 5-10 mg daily

Side Effects: sinus bradycardia, sinus arrest, SA/AV node conductance disturbances, reduction in LVEF, fatigue, depression, exercise intolerance, mask hypoglycemia, withdrawal syndrome

Monitoring:
- HR (Rest: 50-60 bpm –> Exercise: < 100 bpm)
- BP

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7
Q

Carvedilol

A

Coreg

Starting Dose: 6.25 mg BID

Target Dose: 25 mg BID

Side Effects: sinus bradycardia, sinus arrest, SA/AV node conductance disturbances, reduction in LVEF, bronchospasm, fatigue, depression, exercise intolerance, mask hypoglycemia, withdrawal syndrome

Monitoring:
- HR (Rest: 50-60 bpm –> Exercise: < 100 bpm)
- BP

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8
Q

Labetolol

A

Normodyne, Trandate

Maintenance Dose: 200-400 mg BID

Side Effects: sinus bradycardia, sinus arrest, SA/AV node conductance disturbances, reduction in LVEF, bronchospasm, fatigue, depression, exercise intolerance, mask hypoglycemia, withdrawal syndrome

Monitoring:
- HR (Rest: 50-60 bpm –> Exercise: < 100 bpm)
- BP

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9
Q

Metoprolol Tartrate

A

Lopressor

Starting Dose: 25-50 mg BID

Target Dose: 100 mg BID

Side Effects: sinus bradycardia, sinus arrest, SA/AV node conductance disturbances, reduction in LVEF, fatigue, depression, exercise intolerance, mask hypoglycemia, withdrawal syndrome

Monitoring:
- HR (Rest: 50-60 bpm –> Exercise: < 100 bpm)
- BP

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10
Q

Metoprolol Succinate

A

Toprol XL

Maintenance Dose: 100-200 mg daily

Side Effects: sinus bradycardia, sinus arrest, SA/AV node conductance disturbances, reduction in LVEF, fatigue, depression, exercise intolerance, mask hypoglycemia, withdrawal syndrome

Monitoring:
- HR (Rest: 50-60 bpm –> Exercise: < 100 bpm)
- BP

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11
Q

Propranolol

A

Inderal, Inderal LA

Starting Dose: 40 mg BID-TID

Target Dose: 80 mg QID

Side Effects: sinus bradycardia, sinus arrest, SA/AV node conductance disturbances, reduction in LVEF, bronchospasm, fatigue, depression, exercise intolerance, mask hypoglycemia, withdrawal syndrome

Monitoring:
- HR (Rest: 50-60 bpm –> Exercise: < 100 bpm)
- BP

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12
Q

Atorvastatin

A

Lipitor

High Intensity: 40-80 mg daily

Side Effects:
- myopathy (rhabdmomylosis)
- hepatotoxicity

Monitoring:
- LFT/AFT
- CPK
- transglutaminase

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13
Q

Rosuvastatin

A

Crestor

High Intensity: 20-40 mg daily

Side Effects:
- myopathy (rhabdmomylosis)
- hepatotoxicity

Monitoring:
- LFT/AFT
- CPK
- transglutaminase

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14
Q

Captopril

A

Capoten, Captoril

Starting Dose: 6.25-12.5 mg TID

Target Dose: 25-50 mg TID

Side Effects:
- angioedema
- hyperkalemia
- dry cough
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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15
Q

Lisinopril

A

Zestril, Prinivil

Starting Dose: 2.5-5 mg daily

Target Dose: > 10 mg daily

Side Effects:
- angioedema
- hyperkalemia
- dry cough
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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16
Q

Ramipril

A

Altace

Starting Dose: 2.5 mg BID

Target Dose: 5 mg BID

Side Effects:
- angioedema
- hyperkalemia
- dry cough
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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17
Q

Benazepril

A

Lotensin

Starting Dose: 10 mg daily

Max Dose: 40 mg daily

Side Effects:
- angioedema
- hyperkalemia
- dry cough
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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18
Q

Enalapril

A

Vasotec

Starting Dose: 2.5-5 mg daily or BID

Max Dose: 40 mg daily

Side Effects:
- angioedema
- hyperkalemia
- dry cough
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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19
Q

Candesartan

A

Atacand

Starting Dose: 8 mg daily

Target Dose: 32 mg daily

Side Effects:
- angioedema
- hyperkalemia
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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20
Q

Irbesartan

A

Avapro

Starting Dose: 150 mg daily

Target Dose: 300 mg daily

Side Effects:
- angioedema
- hyperkalemia
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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21
Q

Losartan

A

Cozaar

Starting Dose: 25-50 mg once daily

Target Dose: 100 mg daily

Side Effects:
- angioedema
- hyperkalemia
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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22
Q

Olmesartan

A

Benicar

Starting Dose: 20 mg daily

Target Dose: 40 mg daily

Side Effects:
- angioedema
- hyperkalemia
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

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23
Q

Telmisartan

A

Micardis

80 mg daily

Side Effects:
- angioedema
- hyperkalemia
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

24
Q

Valsartan

A

Diovan

Starting Dose: 20 mg BID

Target Dose: 160 mg BID

Side Effects:
- angioedema
- hyperkalemia
- AKI

Monitoring:
- K+
- BUN/SCr
- BP

25
Q

Clopidogrel

A

Plavix

Loading Dose: 600 mg unless on a fibrinolytic

Maintenance Dose: 75 mg daily

Side Effects:
- bleeding
- diarrhea
- rash

Monitoring:
- bleeding

26
Q

Diltiazem

A

Cardizem, Cardizem SR, Cardizem CD, Tiazac, Tiamate, Dilacor XL

Cardizem: 80-120 mg TID

Cardizem SR: 60-120 mg BID

Cardizem CD: 180-360 mg daily

Tiazac/Tiamate: 180-360 mg daily

Dilacor XL: 180-540 mg daily

Side Effects:
- hypotension, facial flushing, dizziness, headache
- reduction in contractility
- constipation
- bradycardia
- AV/SA node conductance disturbances

Monitoring:
- HR
- BP
- constipation

27
Q

Isosorbide Dinitrate

A

Dilinitrate, Isordil

10 mg TID

Side Effects:
- hypotension, facial flushing, lightheadedness, dizziness
- headache

Monitoring:
- reflex tachycardia
- tolerance
- BP
- extreme caution with PDE-I

28
Q

Isosorbide Mononitrate

A

Monoket, Imdur

SL Tablets: 20 mg BID

SR Tablets: 30 mg daily

Side Effects:
- hypotension, facial flushing, lightheadedness, dizziness
- headache

Monitoring:
- reflex tachycardia
- tolerance
- BP
- extreme caution with PDE-I

29
Q

Nitroglycerin

A

SL Tablets: Nitrostat
SL Powder: GoNitro
SL Spray: NitroMist

SL Tablets: 0.3-0.6 mg PRN q5min

SL Powder: 0.4/packet PRN q5min

SL Spray: 0.4/spray PRN q5min

Side Effects:
- hypotension, facial flushing, lightheadedness, dizziness
- headache

Monitoring:
- reflex tachycardia
- tolerance
- BP
- extreme caution with PDE-I

30
Q

Prasugrel

A

Effient

Loading Dose: 60 mg

Maintenance Dose: 10 mg

Side Effects:
- bleeding
- diarrhea
- rash

Monitoring:
- bleeding

31
Q

Ranolazine

A

Ranexa

Maintenance Dose: 500 mg BID –> titrate up to 1000 mg BID over 1-2 weeks

Side Effects:
- constipation
- nausea
- dizziness
- headache

Monitoring:
- drug interactions
- Qtc prolongation
- no effect on HR, BP, perfusion, contractility

32
Q

Ticagrelor

A

Brilinta

Loading Dose: 180 mg

Maintenance Dose: 90 mg BID (12 hours apart)

Side Effects:
- bleeding
- bradycardia
- heart block
- dyspnea (SOB)

Monitoring:
- bleeding
- SOB

33
Q

Verapamil

A

Calan, Isopt, Calan SR, Isopt SR, Covera HS, Velenan

Calan/Isopt: 60-90 mg TID

Calan SR/Isopt SR/ Covera HS/ Velenan: 240 mg daily

Side Effects:
- hypotension, facial flushing, dizziness, headache
- reduction in contractility
- constipation
- bradycardia
- AV/SA node conductance disturbances

Monitoring:
- HR
- BP
- constipation

34
Q

Bivalirudin

A

Angiomax

Bolus Dose: 0.75 mg/kg

Maintenance Dose: 1.75 mg/kg/hr

CrCl < 30 mL/min: 1 mg/kg/hr

Dialysis: 0.25 mg/kg/hr

Side Effects:
- bleeding

Monitoring:
- bleeding

35
Q

Enoxaparin

A

Lovenox

Bolus Dose: 30 mg

Maintenance Dose: 1 mg/kg q12 hr

> 75 yo: 0.75 mg q12 hr

CrCl < 30 mL/min: 1 mg/kg q24 hr

Side Effects:
- low risk for thrombocytopenia
- bleeding

Monitoring:
- bleeding
- CrCl
- platelets

36
Q

Fondaparinux

A

Arixtra

Bolus Dose: 2.5 mg

Maintenance Dose: 2.5 mg subQ q24 h

CrCl < 30 mL/min: contraindicated

Side Effects:
- low risk for thrombocytopenia
- bleeding
- thrombosis

Monitoring:
- bleeding
- CrCl
- platelets

37
Q

Heparin

A

UHF

Bolus Dose:
- 60 units/kg (max: 4000 units)
- 50-100 units/kg during PCI

Maintenance Dose: 12 units/kg/hr
- no maintenance during PCI

Side Effects:
- bleeding
- thrombocytopenia
- osteoporosis (long term)

Monitoring:
- aPTT
- platelets
- bleeding

38
Q

Torsemide

A

Demadex

5, 10, 20 mg qd

39
Q

Sacubitril / Valsartan

A

Entresto

24/26, 49/51 mg

40
Q

Spironolactone

A

Aldactone

12.5 -100 mg qd

41
Q

Rivaroxaban

A

Xarelto

10, 15, 20 mg

42
Q

Simvistatin

A

Zocor

10, 20, 40 mg

43
Q

Pravastatin

A

Pravachol

10, 20, 40 mg

44
Q

Potassium Chloride

45
Q

Quinapril

A

Accupril

10-20 mg qd

46
Q

Omega-3-fatty acid

A

Vascepa, Lovaza, Omytrig

2-4 g qd/BID

47
Q

Hydralazine

A

Apresuline

10, 25, 50 mg QID
Max: 300 mg/day

48
Q

Hydrochlorothiazide

A

Microzide

12.5 - 50 mg qd

49
Q

Furosemide

A

Lasix

20-40 mg BID

50
Q

Fosinopril

A

Monopril

5-10 mg qd

51
Q

Empagliflozin

A

Jardiance

10-25 mg qd

52
Q

Digoxin

A

Lanoxin

125-500 mcg

53
Q

Dapagliflozin

A

Farxiga

5-10 mg qd

54
Q

Chlorothalidone

A

Thalitone

50-100 mg qd

55
Q

Bumetanide

A

Bumex

0.5 - 2 mg qd

56
Q

Eplerenone

A

Inspra

25-50 mg qd

57
Q

Ivabradine

A

Corlanor

2.5, 5, 7.5 mg BID

PHRM 845 Dosing & Substrates (13 decks)

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