Herpesviruses

Question 1

What are the general features of Herpesviruses?

Answer 1

Lecture 18, slide 3

Question 2

What are the different types of Herpesviruses, their features and the types of disease they cause?

Answer 2

Lecture 18, slide 4-5

Question 3

What types of diseases HHV-1 and HHV-2 cause? What is their life cycle?

Answer 3

Lecture 18, slide 6

Question 4

What are some complications of HSV infection?

Answer 4

Lecture 18, slide 11

Question 5

What virus causes chicken pox? Where does it establish latency? Why may it reactivate?

Answer 5

Lecture 18, slide 12, 14

Question 6

What is EBV and its pathogenesis?

Answer 6

Lecture 18, slide 15-16

Question 7

What effect does EBV have on B cells? What are its latency programmes?

Answer 7

Lecture 18, slide 17

Question 8

How does EBV emerge from latency?

Answer 8

Lecture 18, slide 18

Question 9

What genes are expressed in EBVs different latency programmes? What are the roles of the different genes?

Answer 9

Lecture 18, slide 19-20

Question 10

How does EBV switch to lytic replication?

Answer 10

Lecture 18, slide 21

Question 11

What is the pathogenesis of HHV-5?

Answer 11

Lecture 18, slide 22-23

Question 12

How does Herpesvirus evade the immune system?

Answer 12

Lecture 18, slide 24

Question 13

How is Herpesvirus infection treated? How effective is this treatment against the different members of the Herpesvirus family?

Answer 13

Lecture 18, slide 26-27

Question 14

What is a hit and run lytic infection?

Answer 14

Lecture 18, slide 28