Herpesviruses Flashcards
1
Q
Describe herpesviruses
A
linear, dsDNA, icosahedral capsid, enveloped
2
Q
Where do herpesviruses replicate?
A
in the nucleus
3
Q
What is a gammaherpesvirus?
A
EBV and HHV8 (kaposi’s sarcoma)
4
Q
What are three stages of herpesvirus infections?
A
establishment, maintenance, reactivation
5
Q
Which herpesviruses are neurotropic?
A
HSV-1, 2 and VZV
6
Q
Which herpesviruses are lymphotropic?
A
CMV, EBV, HHV-6,7 and KSHV
7
Q
What is treatment of chickenpox?
A
ACV and VZV Ig with steroids
8
Q
What is the cause of roseola(exanthem subitum)?
A
HHV-6 and 7
9
Q
Which strain of herpesvirus are almost 90% of the population seropositive for?
A
HHV-6 and 7
10
Q
What is treatment of shingles?
A
oral ACV and steroids
