Herpes, Influenza, Malaria

Question 1

What are the two most important herpes viruses?

Answer 1

1. Herpes simplex (1 n 2)
2. Varicella-zoster virus

Question 2

Where does Herpes simplex virus work?

Answer 2

Usually
Herpes 1 - mouth, lips

Herpes 2 - Genitals

Treatment has to start within 5 days of appearance of infection.

Question 3

What does varicella-zoster virus cause?

Answer 3

Causes chicken-pox.

Anti-viral treatment must be started within 24hrs of onset of rash; which reduces severity and duration of symptoms.

Question 4

What should be given for those at risk of complications of herpes viruses?

Answer 4

Varicella-zoster immunoglobulin prophylaxis

Question 5

What virus causes shingles and what is the usual protocol for shingles?

Answer 5

Virus - Herpes zoster

Systemic antiviral treatment can reduce severity and duration of pain.

Start treatment within 72hrs of onset rash (continue for 7-10 days)

Question 6

What should immunocompromised and high risk patients be given for shingles?

Answer 6

Parenteral antiviral drug

Question 7

What should be done for chronic pain which persists after the rash has healed?

Answer 7

Refer to a specialist.

Sounds like postherpetic neuralgia.

Question 8

What is the treatment for herpes?

Answer 8

Aciclovir - treatment of choice! But doesn’t eradicate them.

Famciclovir - used for herpes zoster and genital herpes

Valciclovir - used in herpes zoster and simplex; and cytomegalovirus disease after organ transplant