Antibiotic warnings, contraindications and MHRA warning Flashcards

1
Q

Which antibiotics need to be taken before food/empty stomach?

A

DROPFAT - label 23 & 22
Demeclocycline
Rifampicin
Oxytetracycline
Phenoxymethylpenicillin
Flucloxacillin
Ampicillin
Tetracycline

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2
Q

Which antibiotic need to be taken with/after food?

A

Metronidazole
Nitrofurantoin
Pivmecillinam

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3
Q

Which antibiotics can be taken with milk?

A

Doxycycline, lymecycline. minocycline

(Dox Like Milk)

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4
Q

Which antibiotic need to avoid milk?

A

Ciprofloxacin
Demeclocycline
Oxytetracycline
Tetracycline

(C.Dot)

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5
Q

Does amoxicillin have to be taken with or without food?

A

It doesn’t matter.
Food doesn’t affect amoxicillin.

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6
Q
A
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7
Q

What is label 5 and when is it used?

A

Do not take indigestion remedies 2 hours before or after you take medicine

Usually used with enteric coated tablets and Gabapentin.

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8
Q

What is label 6 and when is it used?

A

Do not take indigestion remedies, or medicines containing iron or zinc, 2 hours before or after you take medicine

Usually used with medication containing ofloxacin, some other quinolones, doxycycline, lymecycline, minocycline and penicillamine.

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9
Q

What is label 7 and when is it used?

A

Do not take milk, indigestion remedies, or medicines containing iron or zinc, 2 hours before or after you take medicine

Usually used with medication that contains ciprofloxacin, norfloxacin, tetracyclines that have calcium, iron, magnesium and zinc

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10
Q

What is label 23 and when is it used?

A

Take medicine when stomach is empty. An hour before food or 2 hours after food.

Usually with oral antibiotics.

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10
Q

Which antibiotic can be give in pregnancy/breastfeeding?

A
  • Penicillins
  • Erythromycin - make sure benefit outweighs the risk
  • Cephalosporins
  • Clindamycin
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11
Q

Which antibiotics need to be avoided in pregnancy/breastfeeding?

A
  • Tetracyclines
  • Aminoglycosides
  • Macrolides (except erythromycin)
  • Co-trimoxazole
  • Rifampicin
  • Metronidazole
  • Quinolones
  • Nitrofurantoin
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11
Q

Which antibiotic requires protection against sunlight?
Photosensitivity

A
  • Doxycycline
  • Demeclocycline
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12
Q

What are some important information about flucloxacillin?

A

Causes Cholestatic jaundice & hepatitis

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13
Q

What are some important information about Co-amoxiclav?

A

Causes cholestatic jaundice

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14
Q

What are some important information about Linezolid?

A

Causes blood disorders & optic neuropathy

15
Q

What are some important information about Co-trimoxazole?

A

Causes Stevensons-Johnson syndrome (a severe allergic skin reaction) and blood disorders.

16
Q

What are some important information about Quinolones?

A

Causes tendon damage, arthropathy (joint problems) in children and convulsions with NSAIDs

17
Q

Which antibiotics colour your urine?

A

Rifampicin & Nitrofurantoin - a orange/brown colour.

18
Q

Which antibiotics causes blood disorders?

A
  1. Vancomycin
  2. Trimethoprim
  3. Gentamicin
  4. Co-trimoxazole
  5. Linezolid
19
Q

Examples of blood disorders?

A

Sore throat, fever, malaise, rash, mouth ulcers, bruising or bleeding

20
Q

What are the contraindications of Penicillins?

A

Penicillin allergy

21
Q

What are the contraindications of Tetracyclines?

A

Children under 12 years & pregnant

22
Q

What are the contraindications of Quinolones?

A

History of tendon disorders related to quinolone use

23
Q

What are the contraindications of Aminoglycoside?

A

Myasthenia gravis

24
Q
A