Hepato-biliary surgery Flashcards

1
Q

Across the many different anatomical variations, arteries can do what?

A

go/lie pretty much anywhere they want

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2
Q

What is the most common disease/ surgical problem of the Gallbladder?

A

Gallstone disease

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3
Q

What is Cholesterolosis in the gallbladder? and how does the mucosa appear?

A

There is a buildup of cholesterol esters and they stick to the wall of the gallbladder forming polyps.

‘strawberry gallbladder’ - red with small yellow dots

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4
Q

with Gallbladder polyps, at what size should a polyp be removed?

A

a polyp bigger than 1cm should not stay there. 0-0.5 cm is good.

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5
Q

true or false? you can have gallstones without gallbladder disease

A

true

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6
Q

What is a gallstone made up of?

A

most commonly it is mixed cholesterol and pigment

or you can get cholesterol and pigment ones on their own

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7
Q

Risk factors for gallstones

A

age
gender 9:1 - f:m

cholesterol - obesity, cirrhosis, CF, diabetes, heart transplant

pigment - m=f, haemolytic anaemia (more blood in stools), bile infection like e.coli

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8
Q

how does a patient present with gallstones (7)

A

asymptomatic 70%

dyspeptic symptoms eg flatulent dyspepsia

biliary colic - most common

acute cholecystitis - actual gallbladder becomes enflamed not just colic part

empyema - extreme of cholecystitis - common in diabetic patients due to numbed pain senses

perforation - can be fatal

jaundice

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9
Q

What is Choledocho-lithiasis

A

gallstone in the common bile duct

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10
Q

difference between primary and secondary choledocho-lithiasis?

A

primary - stones form directly in the common bile duct

secondary - originally form in the gallbladder but move to the CBD through cystic duct - more common

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11
Q

what disease can choledocho- lithiasis cause in the pancreas

A

acute pancreatitis

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12
Q

what is obstructive jaundice and what are some symptoms of it?

A

painful effect of choledocho-lithiasis

Pain, jaundice, dark urine, pale stool, pruritus, steatorrhoea

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13
Q

what is Charcot’s triad?

A

combination of:-

  • jaundice
  • fever, usually with rigors
  • right upper quadrant abdominal pain

It occurs as a result of ascending cholangitis (an infection of the bile duct)

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14
Q

Investigations carried out for gallstones? (5)

A

blood tests - liver function test, aspartate aminotransferase - liver damage, lipase, amylase, FBC including white cell count

ultrasound - most common

endoscopic ultrasound

CT scan

oral cholecystography - x ray of gallbladder

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15
Q

Management of gallstones: non-operative (2) and operative methods (7)

A

Asymptomatic – do nothing

Non-operative treatment: Dissolution of gallstone using acid or Lithotripsy - uses shock waves to break up gallstones - they then pass through urine

Operative:
Laparoscopic (camera) cholecystectomy +/- OTC “Gold Standard”

Cholecystectomy - Mini, single port, NOTES (vaginal catheter), total or sub-total

Cholecystostomy

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16
Q

what is the gold standard surgery option for gallbladder removal?

A

Laparoscopic (camera) cholecystectomy +/- OTC (on table cholangiography

17
Q

what is a cholecystostomy?

A

a hole or opening is created in the gallbladder and a catheter is inserted in order to drain the gallbladder

18
Q

management of bile duct stones

A

Lap trans-cystic CBD exploration

Lap exploration of CBD

Open exploration of CBD

endoscopic retrograde cholangiopancreatography either pre, intra or post operation

transhepatic stone retrieval - removal of stones with putting instrument through the liver to reach the bile ducts

19
Q

what is endoscopic retrograde cholangiopancreatography? and when can it be done

A

a procedure that enables you to examine the pancreatic and bile ducts

An endoscope is placed through your mouth and into your stomach and duodenum

can either be done pre, intra or post operatively

20
Q

Name 2 congenital diseases of the biliary tract?

A

Congenital biliary atresia - narrow, blocked or absent bile duct

Choledochal cysts - cystic dilatation of bile ducts

21
Q

what can benign biliary strictures be caused by

A

iatrogenic - due to medical examination or treatment

gallstone related

inflammatory - pyogenic, parasitic, pancreatitis, HIV

22
Q

mirizzi syndrome

A

common hepatic duct obstruction caused by extrinsic compression from an impacted stone in the cystic duct or infundibulum of the gallbladder

Patients can present with jaundice, fever, and right upper quadrant pain

23
Q

What is primary sclerosing cholangitis?

A

long-term progressive disease of the liver and gallbladder characterised by inflammation and scarring of the bile ducts

has potential to turn into cancer - need to monitor

24
Q

Cholangiocarcinoma

A

rare cancer of the bile ducts
chances increases with age

risk factors - Primary sclerosing cholangitis, congenital cystic disease, biliary-enteric draining , carcinogens

25
Intrahepatic cholangiocarcinoma
intrahepatic:- - rare - increasing findings - 3 main types are mass forming, peri-ductal and intra-ductal - surgery is the only option for it
26
presentation of cholangiocarcinoma (3)
obstructive jaundice itching non-specific symptoms
27
investigations carried out for cholangiocarcinoma
Lab Radiology: USS, EUS, CT, MRA, MRCP, PTC, Angiography, FDG PET ERCP, Cholangioscopy and Cytology
28
Management of cholangiocarcinoma
surgical - only curative option palliative - surgical bypass, stenting (percutaneous vs endoscopic), chemo, Photodynamic therapy (PDT), liver transplant - not standart
29
How does Photodynamic therapy work?
a treatment that uses a drug, called a photosensitiser or photosensitising agent, and a particular type of light. When photosensitisers are exposed to a specific wavelength of light, they produce a form of O2 that kills nearby cells
30
gallbladder cancer general info
rare - 2-5% of GI cancers 90% of patients with GC have existing gallstones aggressive, poor prognosis unless caught early. Usually incidental finding through having gallstones treatment depends on stage
31
What does the term peri-ampullary tumours mean
a varied group of neoplasms arising from the head of the pancreas, the distal common bile duct and the duodenum - can have adenomas or adenocarcinomas under this umbrella term
32
treatment options for ampullary tumours
ampulla - an opening into the duodenum ``` endoscopic excision (removal) trans-duodenal excision ``` pancreatico-duodenectomy