Hepatitits Flashcards

1
Q

Are the different hepatitis viruses closely related to each other from an evolutionary standpoint?

A

Nope

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2
Q

Do the different hepatitis viruses cause similar symptoms?

A

Yes because they all infect the hepatocytes

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3
Q

Which hepatitis viruses cause acute hepatitis? How do you treat acute hepatitis?

A

All of them! Treat with supportive care

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4
Q

Which hepatitis viruses are transmitted via the fecal-oral route?

A

A&E

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5
Q

Which hepatitis viruses are transmitted by sex/birth/blood?

A

B,C, & D

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6
Q

Which hepatitis viruses are controlled by vaccines?

A

A, B, & hopefully E

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7
Q

Which hepatitis virus has a high risk for bad outcomes but is dependent on Hep B for coinfection?

A

D

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8
Q

Is Hep B vaccination protective against Hep D?

A

Yes

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9
Q

HepA:

IgM = x

A

x = Acute Infection

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10
Q

HepA

IgG = x

A

x = Recovered/vaccinated

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11
Q

HepB

Viral surface antigen =

A

Acute

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12
Q

HepB

IgG against viral surface antigen =

A

Recovered/Vaccinated

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13
Q

HepC

EIA =

A

Real or False Postitve

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14
Q

HepC

RIBA =

A

Confirmation for Positive EIA

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15
Q

HepD

Delta Antigen =

A

Infection

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16
Q

Which hepatitis viruses can cause chronic infections which can lead to cirrhosis or cancer?

A

B&C

17
Q

How do you treat chronic hepatitis?

A

Polymerase inhibitors and IFN

18
Q

What’s the downside to treatment with Polymerase inhibitors and interferon?

A

Many side effects, often ineffective

19
Q

What new medication may improvement treatment of serotype 1 (HepC)?

A

Protease inhibitors

20
Q

What treatment alleviates liver failure?

A

Transplant

21
Q

Under what circumstances will a transplanted liver become infected with a hepatitis virus?

A

If the virus was not cleared from a secondary site of infection

22
Q

What may help clear infections from secondary sites before liver transplantation?

A

A short course of antivirals

23
Q

What complicates treatment of Hepatitis B and C?

A

HIV infection