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Unit 6: Micro > Camplyobacter, Helicobacter, Listeria > Flashcards

Camplyobacter, Helicobacter, Listeria Flashcards

1
Q

Classify Camplyobacter

A

Curved gram negative rods, microaerophilic

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2
Q

What is the reservoir of campylobacter?

A

Farm animals

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3
Q

Besides diarrhea, what kind of complications may Camplyobacter have?

A

Autoimmune complications

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4
Q

Does campylobacter colonize the small or large intestine?

A

Both!

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5
Q

Is the diarrhea caused by campylobacter secretory or bloody?

A

Bloody due to destructive intracellular infection

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6
Q

After being infected with campylobacter, a patient suffers bacteremia from this bug. What complications may follow bacteremia?

A

Guillain- Barre, reactive arthritis, HUS, meningitis, vascular infection

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7
Q

How do you diagnose campylobacter infection?

A

Microaerophilic culture
Gram stain of fecal smear
Sigmoidoscopy

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8
Q

How do you treat campylobacter infection?

A

Rehydration, add antibiotics if predisposed to complications

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9
Q

What enzyme does H. pylori possess?

A

Urease

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10
Q

How does H. pylori cause a peptic ulcer?

A

Colonizes stomach, irritates stomach lining, attracts a massive inflammatory infiltrate, destroys local cells–> peptic ulcer

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11
Q

What condition does a peptic ulcer predispose you to?

A

Gastric cancer and MALT lymphoma

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12
Q

How do you diagnose peptic ulcer caused by H. pylori?

A

Scope, urea breath test, PCR, biopsy

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13
Q

How do you treat peptic ulcer caused by H. pylori?

A

Triple therapy–> trios of antibiotics

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14
Q

Classify Listeria

A

Gram positive rod, beta hemolytic

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15
Q

Does listeria grow better in the warm or cold?

A

Cold

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16
Q

How is Listeria transmitted?

A

Ingestion of uncooked refrigerated foods or contact with farm animals

17
Q

Is Listeria intracellular or extracellular?

A

Intracellular

18
Q

How does Listeria escape from phagocytic vacuoles?

A

It uses listerolysin

19
Q

How does Listeria transmit from cell to cell?

A

Actin-based motility

20
Q

Will Listeria grow in the placenta?

A

Yes

21
Q

What are complications of infection with Listeria?

A

Complications of pregnancy, neonatal morbidity and mortality, sepsis and CNS infection in immunocompromised patients

22
Q

How do you treat Listeria?

A

Amplicillin and Getamicin or Trimethoprim and Sulfamethoxazole

23
Q

From a GI standpoint, what does listeria cause?

A

Uncomplicated gastroenteritis in a previously healthy individual

24
Q

How should you treat the gastroenteritis caused by Listeria?

A

Rehydrate and Report

Unit 6: Micro (7 decks)

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