Haemophilus and Bordetella Flashcards
Haemophilus and Bordetella only infect one species- which is it?
Human restricted
What type of media do Haemophilus and Bordetella require and what must be present for them to thrive on these cultures?
Chocolate Agar, Factors V and X
How are Haemophilus and Bordetella transmitted?
Respiratory droplets
What patient population is mainly infected by Haemophilus and Bordetella?
Pediatric patients- respiratory infection
Can you vaccinate against Haemophilus and Bordetella?
Yes
Generally speaking, how do you treat Haemophilus and Bordetella?
Antibiotics and Supportive Care
Classify Haemophilus
Gram negative pleomorphic (can appear as cocci, rods, or mixture on microscopy)
Which is more pathogenic, encapsulated or unencapsulated haemophilus? Which is covered by the vaccine? Which causes lethal meningitis?
Encapsulated (Hib)
What invasive diseases follow bacteremia after an upper respiratory infection with Hib?
Meningitis, cellulitis, epiglottitis, septic arthritis
Unencapsulated H. influenzae (NTHi) are less pathogenic because they lack what virulence factor?
Capsule
Is NTHi part of the normal flora?
It may be
Though NTHi lacks a capsule, what virulence factors does it possess and have in common with Hib?
IgA protease, pili, adhesins
What type of disease does infection with NTHi cause?
Neonatal and postpartum sepsis, CF pneumonia, and systemic complications after untreated local mucosal infections
What type of patients are more likely to suffer from the conditions caused by infection with NTHi?
Those with respiratory or immune predisposition
Is B. pertussis highly contagious?
Yes
