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Microbiology 2nd Sem Midterm > Hepatitis Virus > Flashcards

Hepatitis Virus Flashcards

1
Q

Hepatitis A

New genus

A

Heparnavirus

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2
Q

Hepatitis A

Spread by

A

Fecal oral route

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3
Q

Hepatitis A

Incubation period

A

15-50 days

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4
Q

Hepatitis A

Structure

A 
Naked
Icosahedral
\+ Vpg protein
SS+RNA
Only one serotype
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5
Q

Hepatitis A

Replicates in

A

Cytoplasm

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6
Q

Hepatitis A

Interacts with HAVCR1 expressed on

A

Liver and T cells

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7
Q

Hepatitis A

Not cytolytic and released by

A

Exocytosis

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8
Q

Hepatitis A

Liver pathology is

A

Indistinguishable to HBV

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9
Q

Hepatitis A

True or false

Does cause chronic liver disease?

A

False

Also not associated with cancer

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10
Q

Hepatitis A

Symptoms

A

Similar to HBV
Occurs 15-50 days
Wane during jaundice

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11
Q

Hepatitis A

Treatment

A

Prophylaxis with immune serum globulin given before or early in the incubation period

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12
Q

Hepatitis A

Active immunization with

A

Killed HAV for two doses

Booster 6-12 months later

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13
Q

Hepatitis A

Active immunization recommended for

A

Travelers
2-18 years old
Men who have sex with men

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14
Q

Hepatitis A

Serologic test

A

Anti HAV IgM via ELISA or RIA

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15
Q

Hepatitis B virus

A

Major member of hepadnaviruses

Establish chronic infections

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16
Q

Hepatitis B virus

Genome

A

Double stranded DNA

DNA strand is partially complete

17
Q

Hepatitis B virus

Protein

A

HBsAG- glycosylated

HBcAG - polypeptide

18
Q

Hepatitis B virus

Envelope contains

A

HBsAG

Lipid

19
Q

Hepatitis B virus

Replication

A

HBsAG - cytoplasm

HBcAg - nucleus

20
Q

Hepatitis B virus

Structure

A

Enveloped
DS DNA
Reverse transcriptase
Replicates through RNA

21
Q

Hepatitis B virus

Virion

A

Dane particle

22
Q

Hepatitis B virus

Major component of HBsAG particles

23
Q

Produces and release antigenic decoy particles

24
Q

Hepatitis B virus

Major source of infection

25
Q

Hepatitis B virus

Most efficient way to acquire virus

A

Injection of virus into the blood stream

26
Q

Hepatitis A

Formerly

A

In picarnovirus family

Microbiology 2nd Sem Midterm (5 decks)

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