Hepatitis Flashcards

1
Q

What are the causes of hepatitis?

A

Alcoholic hepatitis

NAFLD

Viral Hepatitis

Autoimmune hepatitis

Drug induced hepatitis (e.g paracetamol overdose)

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2
Q

How may hepatitis present?

A
Abdo pain
Fatigue
Pruritis 
Muscle and joint aches
Nausea and vomiting 
Jaundice 
Fever (viral hepatitis)
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3
Q

How is Hep A transmitted?

A

Faecal oral

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4
Q

What type of virus is Hep A?

A

RNA

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5
Q

What is a complication of Hep A?

A

Cholestasis

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6
Q

What type of virus is Hep B?

A

DNA

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7
Q

How is Hep B transmitted?

A

Blood/bodily fluids mainly

Also vertical transmission from mother to child in pregnancy

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8
Q

A patient is positive for HBsAg, HBeAg, IgM anti-HBcAg and IgG anti-HBcAg, what’s going on?

A

Active Hep B infection

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9
Q

A patient is positive for IgG anti-HBsAg, what’s going on?

A

Vaccinated against Hep B

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10
Q

A patient is positive is positive for IgG anti-HBsAg, IgG anti-HBcAg and IgG anti-HBeAg, what’s going on?

A

Cleared Hep B spontaneously

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11
Q

A patient is positive for HBsAg, HBeAg and IgG anti-HBcAg, what’s going on?

A

Chronic Hep B infection, low risk

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12
Q

What is the manager of Hep B infection?

A

Screen for other blood borne viruses

Referral to gastro, hep, or infectious diseases

Notify public health Wales

Stop drinking alcohol and smoking

Educate about reducing transmission

Test for complications I.e fibroscan for cirrhosis

Antiviral meds

Liver transplant for end stage disease

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13
Q

What type of virus is Hep C?

A

RNA

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14
Q

What are the two completely of Hep C?

A

HCC

Liver cirrhosis

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15
Q

What is the manager of Hep C?

A

Same as Hep B

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16
Q

What type of virus is Hep D?

A

RNA

17
Q

What is the virus type in Hep E

A

RNA

18
Q

How is Hep E spread?

A

Faecal oral

19
Q

What types of hepatitis have vaccines available?

A

Hep A, Hep B

20
Q

What are the two types of autoimmune Hep and what groups do they occur in?

A

Type 1: adults

Type 2: children (teenage/early 20’s)

21
Q

What autoantibodies are seen in type 1 autoimmune Hep?

A

Anti-nuclear

Anti-smooth muscle

Anti soluble liver antigen

22
Q

What autoantibodies are seen in type 2 autoimmune Hep?

A

Anti-liver kidney microsomes-1

Anti-liver cytosol antigen type 1

23
Q

How is autoimmune Hep diagnosis confirmed?

A

Liver biopsy

24
Q

What is the treatment for autoimmune Hep?

A

High does Prednisone and azothioprine

Liver transplant last resort and autoimmunity can reoccur after a transplant