Hepatic System: Cholelithiasis and Bile Duct Issues Flashcards
What is Cholelithiasis?
• The presence of gallstones in the gallbladder
What is Choledocholithiasis?
• The presence of at least one gallstone in the common bile duct
What is Cholangitis?
• Redness, inflammation of the bile duct system
What is Cholecystitis?
• Redness, inflammation of the gallbladder
What is a Cholecystectomy?
• Removal of the gallbladder
What causes gallstones to form?
- Gallstones may form if bile contains too much cholesterol, too much bilirubin, or not enough bile salts.
- They may also form if the gallbladder does not empty completely or often enough
What are the 5 F’s that are risk factors for gallstones?
- Fair
- Fat
- Forty
- Fertile
- Female
Why is fertility a factor in gallstone formation?
• Increased estrogen is thought to increase cholesterol levels in bile and decrease gallbladder contraction
What are the clinical manifestations of cholelithiasis?
- 30 mins after eating there will be complaints of
- Pain in the URQ
- Fullness, abdominal distension, may occur after fatty meal
- N/V
- Leukocytosis
- Sometimes fever
- Pain in the URQ
When would acute s/s occur and what are they?
- They would occur with inflammation, obstruction or infection of the biliary organs.
- S/S
- Fever
- Palpable abdominal mass
- Severe URQ pain that radiates back or to the right shoulder
- N/V
What is biliary colic?
- Biliary colic is a common presentation of a stone in the cystic duct or common bile duct of the biliary tree.
- Colic refers to the type of pain that “comes and goes,” typically after eating a large, fatty meal which causes contraction of the gallbladder.
- However, the pain is usually constant and not colicky.
When do biliary colic episodes of severe pain with N/V usually occur?
- Several hours after a heavy meal
What are two diagnostic tests for cholelithiasis?
- CT scan
- Murphy’s sign
Explain Murphy’s Sign.
- Murphy’s sign is elicited in patients with acute cholecystitis by asking the patient to take in and hold a deep breath while palpating the right subcostal area.
- If pain occurs on inspiration, when the inflamed gallbladder comes into contact with the examiner’s hand, Murphy’s sign is positive
What are two drugs used to dissolve small gallstones?
- Ursodiol (on the drug list!)
- Chenodiol
What is the cause of Cholangitis?
- Choledocholithias
What is Charcot’s triad?
- Charcot’s triad is the manifestation of biliary obstruction with upper abdominal pain, fever and jaundice.
What can Charcot’s triad advance to?
- Raynaud’s pentad