Hemotology Flashcards
Microcytic Anemia with low ferritin, low iron, High TIBC and High RDW
Iron deficiency Anemia
Microcytic Anemia with Normal TIBC and Normal Ferritin
Thalassemia; Decreased a or B Hgb chains
Name five neurological findings with Pernicious Anemia
Paresthesia, Loss of Vibratory sense, Loss of fine motor control, Positive Romberg, Positive Babinski
Folic Acid Deficiency differs from Pernicious Anemia how?
Pernicious or B12 deficiency anemia has neuro findings
Identify this anemia: Pt. complains of SOB Heart racing, fatigue, Nails are pale and canker sores. “I feel that my tongue is making it hard to breath”
Aphthous Ulcers or Canker sore is associated with Folic acid deficiency. Although Glossitis is present for both pernicious and folic acid deficiency
What lab results affirms Pernicious anemia
Anti-If (Intrinsic factor) and anti parietal cell antibody test
Nutritionally deficient homeless individuals, eating disorder patients, and substance use patients have a higher risk of developing this anemia
Folic Acid deficiency anemia
Normocytic anemia is associated with low Iron, low TIBC but high ferritin level
Anemia of Chronic disease
Anemia with Joint pain that is associated with stress and dehydration
Sickle Cell Anemia
What are labs associated with Sickle cell anemia
Peripheral smear (SHOWS Sickle), Cellulose acetate and Citrate agar gel electrophoresis (Hgb genotype), Low Hgb
A disorder with excessive amounts of Iron that causes pain on the knuckles of the pointer and middle finger
Hemochromatosis
Treatment for Polycythemia is different from Hemochromatosis? what is the difference
Polycythemia: Phlebotomy and Aspirin, Hemochromatosis: Iron chelation, Avoid Iron rich foods
Most common type of Leukemia in adults, which one is the most common for children
Chronic Lymphocytic Leukemia for Adults; Acute lymphocytic leukemia for children
Hallmark of Chronic Lymphocytic Leukemia
Lymphocytosis; WBC > 30,000
Hallmark of Acute Lymphocytic Leukemia
Pancytopenia
Hallmark of Chronic Myelogenous Leukemia
Philadelphia chromosome
Leukemia is associated with a…
Generalized Lymphadenopathy and weight loss
What is Required to confirm the Diagnosis of Leukemia; How can you differentiate acute from chronic Leukemia
Bone marrow aspiration is needed to confirm diagnosis; Peripheral smear differentiates acute to chronic leukemia
Stage the Lymphoma: Liver and Bone marrow involvement
Stage IV
Stage the Lymphoma: More than one lymph node group, Confined to one side of diaphragm
Stage II
Stage the Lymphoma: Lymph nodes of spleen involved and both sides of diaphragm
Stage III
Stage the Lymphoma: Localized in one lymph node group
Stage I
This type of lymphoma spreads in a predictable fashion along the lymph node groups; Also differentiated by another characteristic
Hodgkin’s Lymphoma; Reed-Sternberg Cells
What medication to start when initiating chemotherapy to reduce tumor lysis syndrome
Allopurinol
Malignant tumors are classified by a system T N M what does each letter signify; Also what is X
T: Size or direct extent of the primary tumor
N: Spread to regional lymph nodes
M: Distant metastasis