Hemostasis Flashcards
1
Q
4 steps of hemostasis
A
1) vascular spasm
2) platelet plug
3) coagulation
4) repair of damage
2
Q
3 roles of thrombin
A
1) activate downstream components of coagulation cascade
2) upstream positive feedback (itself – propagation, VIII and V)
3) paracrine activity which influences hemostasis
3
Q
Thrombin can cause endothelial cells to release
A
NO prostacyclins (PGI2) tPA ADP vWF
