Hemostasis Flashcards
Lifetime of the platelets
5-10 days
Platelets are attracted to collagen and undergo 3 reactions
Adhesion and shape change
Secretion
Aggregation
This is important for the exposure of subendothelium and platelet adhesion
von Willebrand factor
These are clinical signs in a patient with a disorder in their platelets
Petechiae
Ecchymoses
Mucous membrane bleeding
Test for assessment of primary hemostasis
Platelet count (Higher than 30000)
Bleeding count (Normal is less than 4 minutes)
The two most common tests used to evaluate the intrinsic pathway
Activating Clotting Time (ACT)
Activated partial thromboplastin time (PTT)
Normal time for activating clotting time test
Between 60-90 minutes
Extrinsic pathway is evaluated with this test
Prothrombin Time (PT)
Factors X, V, II, and I of the common pathway and factor VII of the extrinsic pathway
There is the breed most commonly affected by a low concentration of the von Willebrand factor
Doberman Pinscher
X linked factor: Hemophilia A y B
Test and the factor deficiency
A VIII
B IX
ACT and PTT elevated
In rodenticide toxicity what tests are important to perform and how they will be
PT and PTT elevated
Common pathway in the coagulation cascade
2 x 5 x 1 = 10
Factors I, II, V, and X
Intrinsic pathway in the coagulation cascade
I shop at Walmart because everything is under $12. Itβs always $11.98
Factors XII, XI, IX and VIII