Hemolytic Disease of a Newborn or HYPERBILIRUBINEMIA

Question 1

A Latin for destruction (lysis) of RBC

Answer 1

Hemolytic

Question 2

Other term for Hyperbilirubinemia

Answer 2

Jaundice

Question 3

What causes the destruction of RBC

Answer 3

A certain degree of lysis of RBC

Question 4

Is present when there is excessive destruction of RBC, which leads to elevated bilirubin level

Answer 4

Hemolytic Disease/Hyperbilirubinemia/Jaundice

Question 5

Is a breakdown of RBC

Answer 5

Bilirubin

Question 6

Secondary to build up of bilirubin

Answer 6

Yellowish sclera and skin

Question 7

The total serum of bilirubin level in the CORD BLOOD

Answer 7

0 to 3 mg/100ml

Question 8

How much of increasing bilirubin level is dangerous for term infants.

Answer 8

20 mg/dl

Question 9

How much of decreasing level is dangerous for preterm infant?

Answer 9

12 mg/dl

Question 10

Invasion of bilirubin into the brain cells

Answer 10

Brain damage

Question 11

How many hours do progressive jaundice occurs

Answer 11

Within 24 hours

Question 12

Other effects of hyperbilirubinemia

Answer 12

Liver and spleen may enlarge
Extreme Edema
Anemia

Question 13

Causes bilirubin to be removed from the body into feces. It initiate early bowel elimination.

Answer 13

Initiation of early breastfeeding

Question 14

Why infants liver processes littler bilirubin in utero

Answer 14

Due to mothers circulation

Question 15

Triggers the liver to assure the function and would speed the conversion potential of liver

Answer 15

Exposure to light

Question 16

Kinds of specialized light for exposure of the infant

Answer 16

Quartz Halogen
Cool White Daylight
Special Blue fluorescent Light

Question 17

How many inches are lights placed above the bassinet or incubator of the infant

Answer 17

12 to 30 inches

Question 18

When does it needed for the term newborn to be scheduled for phototherapy

Answer 18

When total serum bilirubin level rises at 10 to 12 mg/dl at 24 hours of age

Question 19

When does it needed for the preterm newborn to be scheduled for phototherapy

Answer 19

When total serum bilirubin level is lower than 10 to 12 mg/dl

Question 20

Is continuous phototherapy recommended

Answer 20

NO

Question 21

What to cover during phototherapy of the infant

Answer 21

Genitals and Eyes (can cause corneal irritation)

Question 22

Characteristics of infant stools who does undergo through phototherapy?

Answer 22

Bright green due to excessive bilirubin excreted
Loose
Irritating to skin

Question 23

TYPES OF JAUNDICE

Answer 23

Physiologic Jaundice
Pathologic Jaundice

Question 24

Appears 4 to 7 days after birth

Answer 24

Physiologic Jaundice

Question 25

How long do physiologic jaundice lasts?

Answer 25

10 -14 days

Question 26

Bilirubin levels of Physiologic Jaundice

Answer 26

10-12mg/dl at 3 to 4 days

Question 27

It is a clinical Jaundice that appears within the first 24 hours of life

Answer 27

Pathologic Jaundice

Question 28

How many days do pathologic Jaundice lasts?

Answer 28

Over 10 days for term babies

Question 29

Total bilirubin level of pathologic jaundice

Answer 29

Over 12mg/dl

Question 30

Causes of Pathologic Jaundice

Answer 30

Over production or under secretion of bilirubin or Both

Question 31

Two Factors of Hyperbilirubinemia/Jaundice

Answer 31

Increase of bilirubin production
Immature production of proteins by the liver

Question 32

Immature production of protein by the liver can cause?

Answer 32

Decrease in Ligandin and Glucuronyl Tranferase

Question 33

It is a binding protein

Answer 33

Ligandin

Question 34

It is a Conjugating enzymes

Answer 34

Glucuronyl Transferase

Question 35

Percentage of newborn who had jaundice

Answer 35

60%

Question 36

How many percent of the newborns with jaundice are hospitalized for phototherapy

Answer 36

1%