Hemoglobinopathies Flashcards
1
Q
S/Bthal0
A
Can look just like SS, but would expect CBC to look thalassemic (low mcv, high rbc) and increaes A2
2
Q
Hemoglobin Barts
A
Four gamma chains, seen in alpha thal, migrates before the A on capillary electrophoresis
3
Q
Newborn Screen
A
Reports hemoglobins in order of greatest concentration: normal would be FA, SS would be FS
Babies produce start to make A2 months later after birth
4
Q
Sickle Cell Trait
A
Must ALWAYS have more A than S (41%). Without exception. If more S than A, consider transfused SS vs S/Bthal+