Hemoglobinopathies Flashcards

1
Q

S/Bthal0

A

Can look just like SS, but would expect CBC to look thalassemic (low mcv, high rbc) and increaes A2

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2
Q

Hemoglobin Barts

A

Four gamma chains, seen in alpha thal, migrates before the A on capillary electrophoresis

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3
Q

Newborn Screen

A

Reports hemoglobins in order of greatest concentration: normal would be FA, SS would be FS
Babies produce start to make A2 months later after birth

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4
Q

Sickle Cell Trait

A

Must ALWAYS have more A than S (41%). Without exception. If more S than A, consider transfused SS vs S/Bthal+

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