hemoflagellates Flashcards
A different family but go along with other protozoans on phylum sarcomastigophora
hemoflagellates
What family is hemoflagellates
trypanosomatidae
Parasites that are considered medically important
Trypanosoma and Leishmania
Dating nasa phylum sarcomastigophora, ngayon nasa phylum euglinozoa na
hemoflagellates
General structure of hemoflagellates
- fusiform body
- Single nucleus sa gitna
- axonym
- kinetoplast
- flagellum ( sa 3 maliban sa amastigote)
4 morphological forms
- Amastigote - Donovan Leishman
- Promastigote - Leptomonas
- Epimastigote - crithidia
- Trypomastigote
Amastigote
- rounded form of parasite
- non flagellate
- oval form
Promastigote
- flagellated
- seen in vector (iba ibang vector)
- rarely seen in blood
Epimastigote
- fusiform body same as promastigote
- found in arthropod vectors (mosquitoes, fleas, sand flies, lice, fleas, ticks and mites)
Trypomastigote
-contains undulating membrane running along the length of the parasite
- can be seen in vector and blood stream of human host
- Also goes to organ tissues, lymphatic circulations
Amastigote
- also seen in humans
- actively dividing forms of parasite in human host
- nakikita sa cardiac tissue
Generalities of the APET
- All forms are found in trypanosoma cruzi infection
- only epimastigote and trypomastigote can be seen in trypanosoma brucei
- only amastigote and promastigote are seen in Leishmania infections
Trypanosoma is associated with what diseases
- Chaga’s disease (american trypanosomiasis)
- african sleeping sickness/african trypanosomiasis
Trypanosoma multiplies by?
binary fission (asexual reproduction)
Trypanosoma are found in?
Blood, CSF ( in case of severe infection reaching CSF, Lymph nodes/lymphatics.
Diagnosis: of trypanosoma
Microscopic exam, CSF, lymph node aspirate, chancre aspirate, microhematocrit centrifugation, serologic testing, molecular testing ( more specific and sensitive)
Trypanosomiasis occurs mainly in
Africa and South america
Trypanosoma brusei complex
- Causes Trypanosomiasis / African sleeping sickness
Trypanosomiasis/African sleeping sickness affects
- Lymphatic system and CNS
- swollen lymph node at posterior base at neck
Trypanosoma brucei 2 subspecies
- Gambiense
- rhodesiense
Trypanosoma cruzi
Causitive agent for chaga’s disease/American Trypanosomiasis
Trypanosoma cruzi is characterized with
Lesion, conjunctivitis, edema of the face and legs, highly involved with infection of cardiac muscle tissue.
Conjunctivitis caused by trypanosoma cruzi other call
Romaña’ sign/Conjunctivitis
African trypanomiasis is caused by what subspecie
Trypanosoma brucei
Other name of african trypanosomiasis
- african sleeping sickness
Common vector of trypanosomes
Tse tse fly (glossina sp.)
Trypanosomes way of passing
- Mother to child
- sexual contact
- blood transfusion
- mechanical transmission (blood sucking insects)
Infective stage of african sleeping sickness
Metacystic trypomastigote
