hemoflagellates Flashcards

1
Q

A different family but go along with other protozoans on phylum sarcomastigophora

A

hemoflagellates

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2
Q

What family is hemoflagellates

A

trypanosomatidae

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3
Q

Parasites that are considered medically important

A

Trypanosoma and Leishmania

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4
Q

Dating nasa phylum sarcomastigophora, ngayon nasa phylum euglinozoa na

A

hemoflagellates

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5
Q

General structure of hemoflagellates

A
  • fusiform body
  • Single nucleus sa gitna
  • axonym
  • kinetoplast
  • flagellum ( sa 3 maliban sa amastigote)
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6
Q

4 morphological forms

A
  1. Amastigote - Donovan Leishman
  2. Promastigote - Leptomonas
  3. Epimastigote - crithidia
  4. Trypomastigote
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7
Q

Amastigote

A
  • rounded form of parasite
  • non flagellate
  • oval form
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8
Q

Promastigote

A
  • flagellated
  • seen in vector (iba ibang vector)
  • rarely seen in blood
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9
Q

Epimastigote

A
  • fusiform body same as promastigote
  • found in arthropod vectors (mosquitoes, fleas, sand flies, lice, fleas, ticks and mites)
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10
Q

Trypomastigote

A

-contains undulating membrane running along the length of the parasite
- can be seen in vector and blood stream of human host
- Also goes to organ tissues, lymphatic circulations

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11
Q

Amastigote

A
  • also seen in humans
  • actively dividing forms of parasite in human host
  • nakikita sa cardiac tissue
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12
Q

Generalities of the APET

A
  • All forms are found in trypanosoma cruzi infection
  • only epimastigote and trypomastigote can be seen in trypanosoma brucei
  • only amastigote and promastigote are seen in Leishmania infections
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13
Q

Trypanosoma is associated with what diseases

A
  • Chaga’s disease (american trypanosomiasis)
  • african sleeping sickness/african trypanosomiasis
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14
Q

Trypanosoma multiplies by?

A

binary fission (asexual reproduction)

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15
Q

Trypanosoma are found in?

A

Blood, CSF ( in case of severe infection reaching CSF, Lymph nodes/lymphatics.

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16
Q

Diagnosis: of trypanosoma

A

Microscopic exam, CSF, lymph node aspirate, chancre aspirate, microhematocrit centrifugation, serologic testing, molecular testing ( more specific and sensitive)

17
Q

Trypanosomiasis occurs mainly in

A

Africa and South america

18
Q

Trypanosoma brusei complex

A
  • Causes Trypanosomiasis / African sleeping sickness
19
Q

Trypanosomiasis/African sleeping sickness affects

A
  • Lymphatic system and CNS
  • swollen lymph node at posterior base at neck
20
Q

Trypanosoma brucei 2 subspecies

A
  • Gambiense
  • rhodesiense
21
Q

Trypanosoma cruzi

A

Causitive agent for chaga’s disease/American Trypanosomiasis

22
Q

Trypanosoma cruzi is characterized with

A

Lesion, conjunctivitis, edema of the face and legs, highly involved with infection of cardiac muscle tissue.

23
Q

Conjunctivitis caused by trypanosoma cruzi other call

A

Romaña’ sign/Conjunctivitis

24
Q

African trypanomiasis is caused by what subspecie

A

Trypanosoma brucei

25
Q

Other name of african trypanosomiasis

A
  • african sleeping sickness
26
Q

Common vector of trypanosomes

A

Tse tse fly (glossina sp.)

27
Q

Trypanosomes way of passing

A
  • Mother to child
  • sexual contact
  • blood transfusion
  • mechanical transmission (blood sucking insects)
28
Q

Infective stage of african sleeping sickness

A

Metacystic trypomastigote

29
Q
A