Hemodynamics Flashcards
How do you calculate the cardiac output? And what is the normal range?
CO = SV x HR Normal = 4-8 L/min
What is the normal cardiac index?
2.5-4L/min/m2
What is stroke volume (SV) and what happens to CO if SV increases?
Stroke volume is how many mL per beat the left ventricle ejects. It is determined by the preload, afterload, and contractility.
If SV increases the CO increases
normal SV = 50-100ml/beat
How do you measure afterload? What happens to the SV and CO as the afterload increases?
It is measured by the PVR (right ventricle) and SVR (left ventricle)
as afterload increases the SV and CO decrease
What is a normal CVP (aka RAP)?
2-6mmHg
what is a normal pulmonary artery pressure?
30-20/ 15-8
mean <20mmHg
What is a normal PAOP?
8-12 mmHg
what is a normal SVR?
800-1200 dynes/s/cm-5
(MAP -CVP) / CO x 80
What is the normal for PVR?
50-250 dynes/s/cm-5
what is the normal range for mixed venous oxygen saturation (SvO2)?
60-75%
Direct measurement in pulmonary artery
what is the normal for a central venous oxygen saturation (ScvO2)?
> 70%
direct measurement in the superior vena cava
what is the normal arterial oxygen saturation (SaO2)
95-99% on RA
Dopamine at high doses will have an effect on what?
heart rate
Dopamine at high doses (11-20mcg) will increase BP, PAP, PAOP, CO, SV, SVR and PVR
Levophed increases in all aspects of hemodynamics, but what does it have the greatest effect on?
SVR
no changes to HR
Phenylephrine has a hemodynamic effect on which elements?
BP, SV/SI, SVR
Epinephrine increases all aspects of hemodynamics but has the greatest effect on what?
SVR
increases the HR too
Which medications increase your preload?
volume expanders (crystalloid, collids) pressors
Which medications decrease your preload?
Diuretics
Dilators (nitrates, nitroprusside, nesiritide)
Morphine (vasodilates venous bed)
Which medications increase your afterload?
Vasopressors
levo, neo, epi, and at high doses dopamine
Which medications decrease your afterload?
ACE inhibitors Calcium channel blockers IABP Nitroprusside Nitroglycerin at high doses
which medication increase contractility?
Positive inotropes
Dobutamine, Dopamine (5-10mcg/kg/min), Primacor, Epinephrine
Which medications decrease your contractility?
negative Inotropes (Beta blockers, calcium channel blockers) Metabolic problems ( metabolic acidosis, endotoxins of sepsis)
When would you see a “giant V wave” on a PAOP waveform?
During mitral valve insufficiency. This is associated with acute inferior wall myocardial infarction/papillary muscle disfunction/rupture
What happens if you arterial waveform is overdamped?
results in falsely DECREASED SBP and falsely HIGH DBP as well as a diminished or absent dicrotich notch
this may be due to air or blood in the clot system, loose connections, loss of air in the pressure bad, kinking of the catheter/tubing system
What happens if your arterial waveform is underdamped?
results in falsely HIGH SBP and a possible falsely low DBP and “ringing” artifact on the waveform
This may be due to pinpoint air bubbles in the system, add-on tubing, or defective transducer
In cardiogenic shock, all compensatory mechanisms to maintain CO have failed, what hemodynamic profiles do you expect to be elevated in this type of shock?
PAOP and SVR
Elevated left ventricular preload (PAOP) with associated pulmonary symptoms
Elevated left ventricular afterload (SVR) due to vasoconstrictive compensatory mechanisms
A patient is admitted with the following clinical findings: Chief complaint of SOB and fatigue, bibasilar crackles noted with S3 gallop, CT chest illustrated venous congestion and cardiomegaly, weight increase of 20lbs over the last two weeks.
Which of the following hemodynamics is found with this patient and what tx is indicated?
A. increase afterload, decrease contractility, and decrease preload;nesiritide to increase contractility
B. decrease afterload, decrease contractility, and increase in preload; lasix to increase afterload
C. decrease afterload, increased contractility, and increase preload; amiodarone to decrease preload
D. increase afterload, decrease contractility, and increased preload; dobutamine to increase contractility
D
The patient reflects heart failure. To compensate for the reduced cardiac output, a patient in heart failure vasconstricts. Therefore, afterload is high. Due to the low EF, the left heart pressures increase resulting in lung crackles, s3 heart sounds, and increase preload