Hemo-coccidia Flashcards
how does disease result from hepatozoonosis
axesual replication of the parasite in IH
where does hepatozoonosis replicate at in IH
leukocytes in bone marrow, spleen, and lesser extent liver
what is the DH in hepatozoonosis
ticks
where does sexual replication occur hepatozoonosis
in DH! (ticks)
what is the IH for hepatozoonosis
dogs
how are dogs infected with hepatozoonosis
ingestion of ticks w mature oocysts in hemocoel
which infection is more severe H. canis or H. americanum
H. americanum
dogs naturally infected with H.canis are generally
asymptomatic
is there age associated immunity with H.canis
yes
>4-6 months appear resistant to experimental infections
what species of tick is associated with H.canis
rhipicephalus sanguinensis
where does H.canis replicate in IH
asexually in bone marrow
clinical signs H.canis dogs
transient fever, skeletal pain, recumbency
low levels of parasitemia in blood
H.americanum replication in IH
asexually in host striated muscle
elicit inflammatory response
H.americanum species confirmed by
PCR sequence analysis
dogs infected by what to get H.americanum
ingestion of infected amblyomma maculatum
transmission by paratenic host!
t/f for H.americanum developing organisms (merogony) are protected from host immunity while in cyst
true
H.americanum clinical disease
fever, lethargy, neutophilic leukoctosis, non-regenerative anemia, muscle weakness, atrophy of head muscles
H.americanum diagnosis
muscle biopsy of suspected animals
serologic and PCR testing
t/f infection of hepatozoonosis in dogs is lifelong
true
how should you approach treatment of hepatozoonosis
control the disease, not curative
how to prevent hepatozoonosis?
avoidance of tick exposure and predation of paratenic hosts
is hepatozoonosis zoonotic?
NO!
haemosporidia disease is associated with
axesual replication in tissues and blood cells of IH
what is the DH of haemosporidia
ticks
does sexual replication occur in DH or IH haemosporidia?
DH (ticks)
how does IH get infected with haemosporidia
sporozoites transferred to IH by tick during obligate blood meal
piroplasms
pyriform/round/ rod-shaped parasite stages seen in blood
babesia sp disease associated with
non-regenerative anemia from destruction of RBCs
t/f there is limited asexual replication in babesia sp
FALSE, unlimited
what animals are associated with theileria sp disease
livestock
cytauxzoon felis disease associated with
asexual replication in macrophages in spleen and hepatic tissues
clog blood vessels and obstruct blood flow
cytauxzoon felis is universally fatal in what species
domestic cats
what are examples of vertebrae hosts babesia sp affect
dogs, cattle, horses, people
how do ticks become infected with babesia sp
ingestion of merozoites in RBS of IH
can transovarial transmission occur in tick with babesia sp
yes
how IH infected with babesia sp
ticks during obligate blood meal
what is the etiologic agent of texas cattle fever
bovine banesiosis
how does texas cattle fever get transmitted
transovarial transmission to tick offspring allow for one host ticks to transmit disease
how is texas cattle fever controlled
intensive dipping the “one host” tick (rhipicephalus microplus)
what species of babesiosis can infect dogs
B.canis and B. gibsoni
B.canis
priplasms larger and pear shaped
B. gibsoni
piroplasms smaller, oval, signet ring form common
disease in cattle clinical signs babesiosis
pyrexia, anemia, hemoglobinuria, icterus
disease in dogs clinical signs babesiosis
pyrexia, anemia, thrombocytopenia, dysorexia, vomiting, lethargy
diagnosis of babesiosis
piroplasms in blood smeat
serology in IgG Ab
PCR testing and matching gene sequence data
imidiocarb
denatures DNA in babesiosis
t/f infected animals with babesiosis should be considered asymptomatic carriers for life
true
blood donor dogs should be screened for
how to prevent babesiosis
tick control products
timely tick removal
avoid contact fighting with known carriers