Cytauxzoon felis Flashcards
Cytauxzoon felis disease associated with
asexual replication in macrophages in spleen and hepatic tissues
what is obstruction of blood flow and tissue ischemia associated with
engorged leukocytes adhere walls in lumen of veins in various organs
schizonts develop into what?
merozoites
what happens when schizonts develops into merozoites
rupture host cells and infect erythrocytes
parasitemia is
detectable in stained blood smear
late stage disease is associated with
eminent death
what is the natural asymptomatic host for Cytauxzoon felis
bobcats
how does a tick become infected with Cytauxzoon felis
nymphs feed on bobcats, allowed to molt, adult ticks feed on domestic cats
what is the competent vector for Cytauxzoon felis trasmission
amblyomma americanum
feline cytauzoonosis clinical presentation
infected cats often exhibit non specific signs of the disease (acute lethargy, depression, anorexia)
icteric w pale mucous membranes, dehydrated, polydipsic
advanced cases may be
dyspenic w radiographic evidence of severe brochointerstitial pulmonary disease
t/f pyrexia often coincident with parasitemia
true
what are the signs of terminal disease for Cytauxzoon felis
hypothermia, vocalization immediately prior to death
how to diagnose Cytauxzoon felis
hematology
clinical chemistry
parasites detected in host cells
hematology
leukopenia w left shift and toxic change of neutrophils
normochromic, non-regenerative anemia
what is the clinical chemistry of Cytauxzoon felis
hyperbilirubinemia, hyperglycemia
hypoalbuminemia, hypokalemia
how to detect Cytauxzoon felis parasites in host cells
piroplasms in erythrocytes
schizonts in macrophages
what factors can influence Cytauxzoon felis spread
global warming
bobcat populations spreading and increasing
relationship between ticks and bobcat reservoir
factors facilitating spread of bobcat populations
home range necessary for breeding
excess mortality not common for adults
reproductively active through adulthood
prefer areas w rocky shallow soil, broken terrain
sustain healthy tick population
t/f until recently Cytauxzoon felis was considered 100% fatal even with therapeutic intervention
true
what is treatment sucess a function of
when in the disease process treatment is initiated
what therapy is mor effective against Cytauxzoon felis schizonts than Imidiocarb
Atovaquone and Azithromycin
when should treatment of Cytauxzoon felis be initated
any cat presenting with acute lethargy or other classical signs
t/f blood samples should be submitted to confirm dx
true
t/f prevention does not have more promise than a cure
false, it does
how can owners prevent Cytauxzoon felis infection
keep cats indoors
observe for signs of acute disease march-october
