Cytauxzoon felis Flashcards

1
Q

Cytauxzoon felis disease associated with

A

asexual replication in macrophages in spleen and hepatic tissues

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2
Q

what is obstruction of blood flow and tissue ischemia associated with

A

engorged leukocytes adhere walls in lumen of veins in various organs

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3
Q

schizonts develop into what?

A

merozoites

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4
Q

what happens when schizonts develops into merozoites

A

rupture host cells and infect erythrocytes

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5
Q

parasitemia is

A

detectable in stained blood smear

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6
Q

late stage disease is associated with

A

eminent death

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7
Q

what is the natural asymptomatic host for Cytauxzoon felis

A

bobcats

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8
Q

how does a tick become infected with Cytauxzoon felis

A

nymphs feed on bobcats, allowed to molt, adult ticks feed on domestic cats

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9
Q

what is the competent vector for Cytauxzoon felis trasmission

A

amblyomma americanum

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10
Q

feline cytauzoonosis clinical presentation

A

infected cats often exhibit non specific signs of the disease (acute lethargy, depression, anorexia)
icteric w pale mucous membranes, dehydrated, polydipsic

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11
Q

advanced cases may be

A

dyspenic w radiographic evidence of severe brochointerstitial pulmonary disease

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12
Q

t/f pyrexia often coincident with parasitemia

A

true

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13
Q

what are the signs of terminal disease for Cytauxzoon felis

A

hypothermia, vocalization immediately prior to death

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14
Q

how to diagnose Cytauxzoon felis

A

hematology
clinical chemistry
parasites detected in host cells

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15
Q

hematology

A

leukopenia w left shift and toxic change of neutrophils
normochromic, non-regenerative anemia

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16
Q

what is the clinical chemistry of Cytauxzoon felis

A

hyperbilirubinemia, hyperglycemia
hypoalbuminemia, hypokalemia

17
Q

how to detect Cytauxzoon felis parasites in host cells

A

piroplasms in erythrocytes
schizonts in macrophages

18
Q

what factors can influence Cytauxzoon felis spread

A

global warming
bobcat populations spreading and increasing
relationship between ticks and bobcat reservoir

19
Q

factors facilitating spread of bobcat populations

A

home range necessary for breeding
excess mortality not common for adults
reproductively active through adulthood
prefer areas w rocky shallow soil, broken terrain
sustain healthy tick population

20
Q

t/f until recently Cytauxzoon felis was considered 100% fatal even with therapeutic intervention

A

true

21
Q

what is treatment sucess a function of

A

when in the disease process treatment is initiated

22
Q

what therapy is mor effective against Cytauxzoon felis schizonts than Imidiocarb

A

Atovaquone and Azithromycin

23
Q

when should treatment of Cytauxzoon felis be initated

A

any cat presenting with acute lethargy or other classical signs

24
Q

t/f blood samples should be submitted to confirm dx

A

true

25
Q

t/f prevention does not have more promise than a cure

A

false, it does

26
Q

how can owners prevent Cytauxzoon felis infection

A

keep cats indoors
observe for signs of acute disease march-october