Hemmer der Proteinsynthese- Oxazolidone Flashcards

1
Q

Oxazolidone

A
  • Linezolid
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2
Q

Wirkmechanismus:

A
  • hemmt Initiation (50S-Rib)
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3
Q

Wirkspektrum:

A

nur grampositive Keime

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4
Q

Indikationen:

A
  • Multiresistente Erreger bei
    • Pneumonien und
    • HautInfektionen
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5
Q

Nebenwirkungen:

A
  • u.a. Myelosuppression,
  • BB-Veränderungen,
  • Anstieg der Leberwerte und
  • Venenreizung
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6
Q

Wechselwirkungen

A
  • mit tyraminhaltigen Speisen und
  • MAOHemmern,
  • Antidepressiva
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7
Q

Kontraindikationen:

A
  • unkontrollierbare Hypertonie
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