Heme/Onc

Question 1

This has greater than 25% lymphoblasts, positive periodic acid Schiff (PAS) and positive TdT in pre B and T lymphoblasts

Answer 1

ALL

Question 2

Hemolytic anemia, jaundice, and splenomegaly are associated with this.

Answer 2

Hereditary spheroocytosis

Question 3

This type of blood transfusion reaction has fever and chills within 1-6 hours and caused by cytokine accumulation during blood storage

Answer 3

febrile nonhemolytic

Question 4

This has fever, flank pain, hemoglobinuria, renal failure and DIC within 1 hour of transufion, positive direct Coombs, and caused by ABO incompat

Answer 4

acute hemolytic

Question 5

This causes respiratory distress and signs of noncardiogenic pulm edema within 6 hours of transufion, and caused by donor anti-leuk antibodies

Answer 5

transfusion-related acute lung injury

Question 6

This has basophilic stippling and microcytic anemia (MCV less than 80)

Answer 6

lead poisoning

Question 7

This has MCV greater than 110, low reticulocyte, poikilocytosis

Answer 7

B12 or folate deficiency

Question 8

A patient with a breast mass who has a slightly retracted right nipple and fixed mass with 3x3 spiculated mass with coarse calcifications and a core bx showing foamy macrophages and fat globules should be managed like this.

Answer 8

routine follow-up and no intervention (this is fat necrosis which can mimic breast cancer but has coarse calcifications compared to microcalcifications in maligancy)