heme/onc

Question 1

Thrombotic thrombocytopenic purpura

cause?

Answer 1

1)Microangiopathic hemolytic anemia
(fatigue, dyspnea, pallow, jaundice, hemolysis)
2) Thrombocytopenia
3) fever
4) impaired renal function
5) Neuro sx (AMS, delirium , seizure)

Adam TS13 deficiency (protein that cleaves VW factor it accumulates and causes clots

Question 2

Hodgkin lymphoma

Answer 2

elevated LDH
mediastimal lymphadenopathy
pain after alcohol use
elevated eosinophils (pruritis)