Heme Malignancies Flashcards

1
Q

Lymph nodes that are soft, tender, mobile but enlarged suggest…

A

inflammation/infection

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2
Q

Lymph nodes that are firm, rubbery, mobile and enlarged suggest…

A

lymphoma

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3
Q

Lymph nodes that are hard, fixed, non-tender suggest…

A

carcinoma

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4
Q

At what stage of hematopoiesis does lymphoma affect/occur

A

mature lymphocytes (B cells and mature T cells)

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5
Q

Describe leukemia

A

cancer of blood & bone marrow characterized by uncontrolled accumulation of malignant WBC

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6
Q

Describe the etiology of acute versus chronic leukemia

A

also myeloid vs lymphoid

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7
Q

Describe the difference in clinical presentation between acute and chronic leukemia

A
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8
Q

Describe the diagnosis of leukemia

A
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9
Q

Describe the risk factors for the different forms of leukemia (acute v chronic & myeloid v lymphoid)

A
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10
Q

Describe the etiology of acute myeloid leukemia and the common emergencies within

A
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11
Q

Describe the presentation of acute myeloid leukemia

A
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12
Q

Describe the presentation of tissue infiltration in AML

A
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13
Q

Describe the presentation of leukostasis in AML

A
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14
Q

Describe the presentation of disseminated intravascular coagulation in AML

A
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15
Q

Describe the presentation of tumor lysis syndrome in AML

A
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16
Q

Describe the treatment of AML

A
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17
Q

Describe the treatment for leukostasis in AML

A

leukapheresis & emergent initiation of chemo

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18
Q

Describe the treatment for DIC in AML

A

replace clotting factors and platelets & start chemo

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19
Q

Describe the treatment of tumor lysis syndrome in AML

A

hydrate, allopurinol to clear uric acid, dialysis as needed

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20
Q

Describe the etiology of acute lymphoblastic leukemia

A
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21
Q

Describe the presentation of ALL

22
Q

Describe the treatment for ALL

23
Q

Describe the etiology of chronic myeloid leukemia

24
Q

Describe the presentation of CML

25
Describe the treatment for CML
26
Describe the etiology of chronic lymphoid leukemia
27
Describe the presentation of CLL
28
Describe the treatment for CLL
29
Describe the etiology of lymphoma (Hodgkin & Non-Hodgkin)
30
Describe the presentation of lymphoma
31
Describe the diagnostics for lymphoma
32
Describe the staging of lymphoma
33
Describe the etiology of myeloma
34
Describe the etiology of monoclonal gammopathy of uncertain significance (MGUS)
35
Describe the etiology of multiple myeloma
36
Describe the presentation of multiple myeloma
37
Describe the diagnosis of myeloma
38
Describe the treatment for myeloma
39
Describe the etiology of myelodysplastic syndromes (MDS)
40
Describe the presentation of MDS
41
Describe the diagnosis of MDS
42
Describe the treatment of MDS
43
Describe the etiology of myeloproliferative neoplasms
44
Describe the presentation & complications of MPN
45
Describe the diagnosis of MPN
46
Describe the treatment of MPN
47
Describe the etiology of aplastic anemia
48
Describe the presentation & diagnosis of aplastic anemia
49
Describe the treatment of aplastic anemia
50
What are some complications of aplastic anemia
development of myelodysplastic syndromes or acute myeloid leukemia