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Step 1 > Heme & Chemo Pharm > Flashcards

Heme & Chemo Pharm Flashcards

0
Q

Acts on G2 phase

A

Bleomycin and etoposide

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1
Q

Acts on G2 and S phase

A

Etoppside

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2
Q

Direct factor X inhibitors

A

Apixaban

Rivaroxiban

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3
Q

Direct factor Xa inhibitors CU

A

Prophylaxis of DVT and PE (rivaroxiban)

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4
Q

What is particularly dangerous about direct Xa inhibitors

A

No antidote

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5
Q

ADP receptor inhibitors

A

Clopidogril
Ticlopidine
Presugrel
Ticagrelor

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6
Q

ADP receptor inhibitors MOA

A

Irreversible blocking ADP receptor

> > prevent gp2/3 binding to fibrinogen

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7
Q

Ticlopidine SE

A

ADPr antagonist

Neutropenia

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8
Q

Phospdiesterase 3 inhibitors

A

Cilostazol

Dipyridamole

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9
Q

Cilostazol, dipyridamole CU

A

Intermittent claudication, coronary vasospasm, prophylaxis stroke or TIA, angina prophylaxis

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10
Q

GP IIb/IIIa inhibitors

A

Abciximab
Eptibatide
Tirofiban

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11
Q

Abciximab structure

A

Fab fragment

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12
Q

Non-Hodgkin tx

A

CHOP

cyclophosphamide
Hydroxydaunorubicin
Oncovin
Prednisone

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