Hematuria Flashcards

1
Q

microscopic hematuria defined as?

A

3 or more RBCs per high-power field

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2
Q

should urinalysis be used as a screening tool for bladder cancer?

A

NO; not strong enough

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3
Q

what test is sufficient to warrant a referral for hematuria?

A

microscopy of urine sediment (dipstick must be followed up with this to confirm)

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4
Q

causes of false positive urine dipstick

A

cleansing agent contam, urine pH very high, myoglobin from rhabdo, semen

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5
Q

if suspect glomerular cause of hematuria, what should you do next?

A

check serum Cr and eGFR (low GFR is sign of nephrologic cause)

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6
Q

if GFR is less than 60, don’t use?

A

contrast

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7
Q

if GFR is less than 30, don’t use?

A

Gadolinium (severe allergic rxn)

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8
Q

common causes of gross hematuria

A

UTI, urologic ca, bladder ca, BPH, kidney stones

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9
Q

who is at increased risk of urologic ca?

A

age 35-50, smoking hx, gross hematuria, voiding sx, chemical or drug exposure (cyclophosph, analgesics, Danube river), pelvic radiation

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10
Q

urologic evaluation of hematuria based on eGFR

A

greater than 60 = CT urogram; 30-60 = MR urogram; <30 = non-contrast imaging + retro pyelogram

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11
Q

urine cytology NOT recommended for gross hematuria

A

FREEBIE

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12
Q

follow-up guidelines for a pt with hematuria and initial negative evaluation

A

annual urinalysis/microscopy for the next 2 years at least

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13
Q

why are acanthocytes more specific than dysmorphic RBCs?

A

urine pH and osm can cause dysmorphic RBCs

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14
Q

T/F: a single episode of hematuria is sufficient to warrant a referral.

A

true!

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15
Q

does anticoag therapy change evaluation of hematuria?

A

NO

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16
Q

when should you call a nephrologist?

A

acanthocytes, decreased GFR, high urine protein:creat ratio, fast rise in creatinine (most critical), assoc systemic sx

17
Q

causes of GN with low complement levels

A

membranoproliferative, post-infectious, SLE

18
Q

specific studies to check for membranoproliferative GN

A

Hep C, SPEP, serum free light chains

19
Q

who should get a kidney biopsy?

A

progressive worsening of kidney function, systemic dz (for management), gross proteinuria

20
Q

initial eval of nephrologic hematuria includes?

A

assessment of GFR, proteinuria, serologic studies, kidney US