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Lab Diagnosis 1 > Hematopoiesis, Erythropoiesis, & Bilirubin (Quiz 1) > Flashcards

Hematopoiesis, Erythropoiesis, & Bilirubin (Quiz 1) Flashcards

1
Q

What is hematopoiesis/hemopoiesis?

A

-production and development of all blood cells
-immature precursor cells develop into mature blood cells in the bone marrow
-all cellular blood components derived from hematopoietic stem cells

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2
Q

hemato=

A

blood, cells

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3
Q

poiesis=

A

production

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4
Q

In embryonic development, the bone marrow derived from mesenchymal tissue from the the….

boards q

A

mesoderm

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5
Q

The hemopoietic system is involved in production, maturation, and destruction of blood. What organs are a part of this system?

A

-bone marrow
-thymus
-liver
-spleen
-lymph nodes

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6
Q

omni=

A

whole

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7
Q

Which stem cells can give rise to any of the 220 cell types found in an embryo and occur for only a limited time in early mammalian embryos?

A

totipotent/omnipotent stem cells

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8
Q

pluri=

A

many

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9
Q

Which stem cells can give rise to all cell types that make up the body, except the placenta?

A

pluripotent stem cells

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10
Q

Which stem cells can develop into a limited number of cell types in a particular lineage and are found in bone marrow?

A

multipotent stem cells

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11
Q

uni=

A

one

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12
Q

Which stem cells have a limited ability to differentiate and are committed to making one type of cell?

A

unipotent stem cells

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13
Q

Which stem cells are an immature cell that can develop into all types of blood cells: WBCs, RBCs, platelets/thrombocytes, and have the property of self renewal and, through cell division and differentiation, form populations of progenitor cells that are committed to the main marrow cells lines?

A

hematopoietic stem cells

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14
Q

Is bone marrow vascular or avascular?

test q

A

highly vascular

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15
Q

What is the main function of bone marrow?

A

produce blood cells and store fat

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16
Q

What are the 2 types of bone marrow?

A

red and yellow

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17
Q

Do kids have mostly red or yellow bone marrow?

A

red

18
Q

Do adults have mostly red or yellow bone marrow?

A

yellow

19
Q

Which bone marrow is considered active?

A

red marrow

20
Q

Which bone marrow is considered inactive?

A

yellow marrow

21
Q

What stem cells are found in red marrow?

test q

A

hematopoietic stem cells

22
Q

What are the adult sites of hematopoiesis?

test q

A

bone marrow of:
-skull
-ribs
-sternum
-vertebral column
-pelvis
-proximal ends of femur

23
Q

Which bone marrow helps spleen and liver to remove old damaged cells from circulation?

A

red marrow

24
Q

Which bone marrow has mostly adipose cells?

A

yellow marrow

25
Q

T/F: when blood supply is extremely low, yellow marrow can be converted to red marrow

A

true, this happens in patients with hemolytic anemia, chronic blood loss, or aplastic anemia

26
Q

After what age does yellow marrow begin to convert to red marrow?

A

7 y/o

27
Q

extra=

A

outside

28
Q

medullary=

A

bone marrow

29
Q

What is extramedullary hematopoiesis?

test q

A

hematopoiesis that occurs outside of bone marrow

30
Q

When is it normal to have extramedullary hematopoiesis?

test q

A

during the embryonic period because of the yolk sac, which will turn into liver

31
Q

If someone does have extramedullary hematopoiesis, what are the organs involved?

A

spleen, liver, and lymph nodes

32
Q

What is erythropoiesis?

A

production of RBCs

33
Q

Erythropoiesis is stimulated by what?

test q

A

decreased oxygen in circulation (hypoxia)

34
Q

What are some causes of hypoxia?

A

-high altitude
-blood loss
-respiratory distress like COPD or choking

35
Q

What is the abbreviation for erythropoietin (hormone that stimulated BM to produce RBCs)?

A

EPO

36
Q

Where is EPO produced?

test q

A

kidney

37
Q

Hypoxia is sensed first by what organ?

A

kidney

38
Q

EPO is produced and secreted by kidney. EPO then stimulated what to produce RBCs?

quiz 1 q

A

bone marrow

39
Q

If EPO is stimulated when it is not needed then this person has…

A

a benign or malignant tumor which can cause secondary polycythemia/compensatory polycythemia

40
Q
A

Lab Diagnosis 1 (4 decks)

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