Hematopoiesis Flashcards
Embryonal stage production in _______
yolk sac
Fetal stage (___ -____ months) in _____
2-7 mo, liver, spleen
Early childhood production in ____
long bones –> transitions to axial bones by teens
Axial bones include ___, ___, ___, ___, ____
vetebrae, pelvis, sternum, ribs, skull
Hematopoietic stem cells –> _________ cells –> _________ cells –> Mature cells
progenitor cells; precursors
lymphoid includes
T cells, B cells, NK cells, and precursors
Myeloid cells includes
Non-erythroid/non - lymphoid linages from marrow; Often (granulocytes, monocytes), megakaryocytes, platelets
Life span of erythrocytes
120 days
Pluripotential stem cell can make _________, and _______
self renewal (daughter self); progenitor cells
Pluripotential stem cells includs (CFU-X)____ and ____
CFU-GEMM and CFU-L
(granulocytes/erthroid, monocytes, megakaryocyte); Lymphoids
CFU = colony forming units
Progenitor cells are ____committed to differentiate along one or at most two linages
irreversibly
CFU - GM
CFU granulocyte/macrophage
CFU - M
monocyte
CFU-E
Erthroid
CFU-Meg
megakaryotes