Hematopoiesis Flashcards
Process of blood cell formation
Hematopoiesis
Classical marker of hematopoietic stem cells
a. CD 35
b. CD 7
c. CD 20
d CD 34
d. CD 34
suggests that all blood cells are derived from a single progenitor stem cell called a
pluripotential stem cell
- most widely accepted theory among experimental hematologists
a. Polyphyletic theory
b. Monophyletic theory
Monophyletic Theory
Three phases of Hematopoiesis:
- Mesoblastic/Megaloblastic
- Hepatic.
- Intramedullary/Medullary/Myeloid
Chief site of hematopoieisis in Megaloblastic/Mesoblastic
Yolk sac
1st blood cell
Primitive erythroblasts
Primitive erythroblasts is formed during the first_____ to ______ weeks of life
formed during the first 2 to
8 weeks of life
_______ is the predominant hemoglobin during hepatic phase
Hb F
First fully developed organ in FETUS
Thymus
Hematopoiesis starts in the
bone marrow cavity before the
________month of fetal development
5th month of fetal development
process of replacing red marrow by yellow marrow during development
RETROGRESSION
between ____and ______years of age, adipocytes become more abundant and start to
occupy the spaces in the long bones previously dominated by active marrow
5 and 7 years of age
LARGEST of the secondary lymphoid organs
Spleen
Preferred site for BM aspiration in Adults
Posterior superior iliac crest
Anterior superior iliac crest
Preferred site of BM aspiration in Children (<2 y.o.)
Anterior medial surface of the tibia
