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mtap 2 hema 1 > HEMATOPOIESIS > Flashcards

HEMATOPOIESIS Flashcards

1
Q

Process of blood production (building up of blood components– RBC, WBC, and platelets)

A

Hematopoiesis

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2
Q

INTRAUTERINE HEMATOPOIESIS PHASES (3)

A

Mesoblastic Phase
Hepatic Phase
Myeloid/ Medullary Phase

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3
Q

YOLK SAC

A

Mesoblastic Phase

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4
Q

LIVER

A

Hepatic Phase

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5
Q

RED BM

A

Myeloid/ Medullary Phase

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6
Q

Mesoblastic Phase Begins at

A

19th day of gestation

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7
Q

Hepatic Phase Begins at

A

6 weeks of gestation

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8
Q

Myeloid/ Medullary Phase Begins around

A

5th month of gestation

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9
Q

first cell and doesn’t disappear even until adulthood

A

Primitive Nucleated Erythroblast

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10
Q

Embryonic Hgb (3)

A
  1. Gower I
  2. Gower II
  3. Portland
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11
Q

Production of red blood cells, granulocytes, monocytes, and megakaryocytes

A

Hepatic Phase

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12
Q

Alpha and gamma globin chain production (HbF)

A

Hepatic Phase

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13
Q

Bone marrow producing mainly granulocytes

A

Myeloid/ Medullary Phase

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14
Q

6th months of age gamma-beta globin chain switch

A

Myeloid/ Medullary Phase

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15
Q

80-90% of bone marrow is ACTIVE BONE MARROW

A

Newborn

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16
Q

60% of bone marrow is ACTIVE

A

Young Adult (Age 20)

17
Q

Older Adult: ___ bone marrow is ACTIVE AND ___ is FAT

A

40% ; 60%

18
Q

it is the ratio of marrow cells to fat (red marrow/yellow marrow)

A

CELLULARITY

19
Q

marrow has 30-70% hematopoietic cells

A

Normocellular

20
Q

marrow has >70% hematopoietic cells

A

Hypercellular/ Hyperplastic

21
Q

marrow has <30% hematopoietic cells

A

Hypocellular/ Hypoplastic

22
Q

marrow has few or no hematopoietic cells

A

Aplastic

23
Q

It is the ratio of granulocytes and their precursors to nucleated erythroid precursors

A

M:E (Myeloid: Erythroid) Ratio

24
Q

Normal M:E Ratio

A

3:1 or 4:1

25
Q

_____ and _____ are excluded from the M:E ratio

A

Lymphocytes and monocytes

26
Q

simply counting the # of types of WBC

A

Differential Count Smear

27
Q

special request to identify RBC morphology, especially blast cells

A

PBS

27
Q

Contains both alpha and beta polypeptide chain

A

globin

28
Q

semi-permeable so electrolytes can pass through

A

Cell membrane

mtap 2 hema 1 (9 decks)

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