ANEMIAS Flashcards
Impoverished condition of the blood caused by reduction in RBC, Hgb, or BOTH
ANEMIAS
Anemia is considered to be present if the hemoglobin conc. of the hematocrit is below the lower limit of the 95% reference interval for the individual’s ___, _____, and ____
age, sex, and geographic location
Anemias is defined as a decrease in _________ → resulting in decreased oxygen delivery to the tissues
erythrocytes and hemoglobin
Anemias can be classified morphologically using (2)
○ RBC indices (MCV, MCH, MCHC)
○ Etiology/ Cause
_____ is more accurate than MCH
MCHC
Anemia is suspected when the hemoglobin level is
<12 g/dL in men or <11 g/dL in women
Anemia is mainly caused by: (2)
○ Decreased RBC production
○ Increased RBC destruction
problems in site of production in long bones
Decreased RBC production
healthy BM, but are easily destroyed (e.g. thalassemia)
Increased RBC destruction
Total production of RBC
Total Erythropoiesis
Total production of RBC & can be measured through: (3)
–M:E ratio
–Fecal urobilinogen
–Plasma iron Turnover
Production of RBC that reaches the circulation of peripheral blood (it reaches its lifespan of 120 days)
Effective Erythropoiesis
Effective Erythropoiesis Measured through:
–RBC Turnover Utilization of Iron
–RBC Lifespan
–Reticulocyte Count
GENERAL CLINICAL SIGNS & SYMPTOMS OF ANEMIA (7)
- Low hemoglobin concentration & Blood Volume
- Fatigue
- Dyspnea on exertion
- Faintness
- Vertigo
- Palpitation
- Headache