ADDITIONAL Flashcards
Affects both erythrocytes and metabolic pathways of iron-dependent tissue enzymes
Iron Deficiency Anemia
Iron Deficiency Anemia
Results from conditions leading to chronic gastrointestinal blood loss, including: (5)
○ Long term use of nonsteroidal inflammatory medication
○ Gastritis
○ Peptic ulcer disease
○ Gastropharyngeal reflux disease
○ Angiodysplasia
impaired heme synthesis and abnormal globin synthesis
Sideroblastic anemia
defective DNA synthesis; results in ineffective erythropoiesis (deficiency of vitamin B12 and folate)
Megaloblastic anemia
● Megaloblastic Anemia In 5-10% of elderly
● Attributed to inadequate intestinal absorption of found bound vitamin B12 and pernicious anemia
Vitamin B12 Deficiency
bacterial growth: Helicobacter pylorI
Loss of gastric acid
Develops from inadequate dietary intake
Folate Deficiency
in Folate Deficiency, ___________ are more prone because alcohol interferes with folate absorption
Alcoholic elderly
Shortened RBC survival time
Also results from collagen vascular disease, infections, chronic lymphocytic leukemia
Hemolytic Anemia
high doses of antibiotics, non steroidal inflammatory drugs, quinidine, phenacetin, etc.
Drug induced haemolytic anemia
Hemolytic anemia major types (3)
- Caused by immunologic mechanisms
- Due to intrinsic effects
- Resulting from extrinsic factors