Hematology Week 1: Transfusion Medicine Flashcards by Jay Sandoval

Q

Question 1

A

B 17 years old

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Q

Question 2

A

A IgM

IgM is large and can fix complement as well as cause vascular hemolysis

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Q

Question 3

A

D Group AB

because it is plasma

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Q

ABO Blood Groups

A

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Q

ABO Inheritance

A

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Q

Prevalence of ABO Types

A

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Q

Blood Components

A

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Q

Indications for RBC Transfusion

A

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Q

Non emergency Indications for RBC Transfusion

A

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Q

Question 4

A

2 units

because 1 unit of RBCs 1g/dL increase

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Q

RBC Post-transfusion Increment

A

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Q

Plasma

A

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Q

Indications for plasma transfusion

A

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Q

Platelets

A

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Q

Indications for Platelet Transfusion

A

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Q

Platelet dysfunction indications for platelet transfusion

A

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Q

Cryoprecipitate

A

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Q

Cryoprecipitate contents and storage

A

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Q

Indications for Cryoprecipitate

A

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Q

Question 5

A

RBCs

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Q

Question 6

A

B Platelet dysfunction

Bernard-soulier platelet dysfunction

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Q

What is needed to know to safely transfuse?

A

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Q

Question 7

Sarah is O neg

Derek is AB neg

A

No

because her whole blood has anti A and anti B antibodies

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Q

can a group O mom give birth to a AB child

A

NO

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Q

Question 8

A

D dog

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Q

Rh Blood Group

A

Q

Biggest Clinical concerns of RhD

A

Q

Required testing for RBC Transfusion

A

Q

Agglutination reactions

A

Q

Front type & Back Type of ABO typing

A

Front type is patient RBCs

Back Type is patient plasma

Q

Antibody screen

A

Q

Antibody screen process

A

incubate with anti IgG

Agglutination rxn is positive

Q

RBC Antibody screen

A

Q

Antibody screen clinical significance and caveats

A

Q

Crossmatch

A

Q

Direct Crossmatch

A

Q

Direct Antiglobulin test

A

DAT

Q

DAT indications

A

Q

How DAT works?

A

Q

Question 9

A

D

O- blood with AB plasma

Q

Question 10

A

C

A+ blood with A plasma

Q

O- RBC

A

Q

Emergency Release RBCs

A

Q

Emergency Release Plasma

A

Q

HDFN AKA

A

Hemolytic Disease of the Fetus and Newborn

Q

HDFN

A

Q

Why is IgG helpful to pass to the fetus?

A

Q

The second most common cause for HDFN

A

Q

HDFN PAthogenesis

A

Q

Prevention of Anti-D HDFN

A

Q

Question 11

A

D

K antibodies cross the placenta and attack fetal erythroblasts with resultant anemia

Actually, attack erythroblasts in the bone marrow and can be very devastating

Q

Leukocyte Reduction

A

Q

Product Modifications

A

Leukocyte Reduction

Q

Reduce risk of CMV transmission through transfusion

A

Leukocyte reduction

Q

Irradiating Blood Products

A

Q

GVHD Mortality

A

>90%

Q

Indications for irradiation

A

Q

Transfusion take-home points

A

Q

Question 12

A

D

100,000

Q

Question 13

A

C

20-24 *C 5 days

Q

What is stored at 20-24 *C for 5 days?

A

Platelets

Q

What is stored at 1-6 *C for 5 days?

A

RBCs

Q

What is stored at -18 *C for 1 year?

A

Cryoprecipitate or plasma

Q

Question 14

A

D

Transfusion-associated GVHD

Danger of family member transfusion isthat we may not recognize their cells are foreign but theirs might