Hematology System

Question 0

Plasma minus clotting factors

Answer 0

Serum

Question 1

General Function of Blood

Answer 1

Vehicle of transport
Regulation of pH and ion composition
Defense
Stabilization

Question 2

Composition of Plasma

Answer 2

Water: 90%
Proteins: 8%
Inorganic salts: 1%
Lipids: 0.5%
Sugar: 0.1%

Question 3

Essential component of clotting system

Answer 3

Blood coagulation proteins

Question 4

Major contribution to osmotic pressure of plasma

Answer 4

Albumin

Question 5

Proteases, antiproteases, transport protiens

Answer 5

Alpha globulin

Question 6

Transferrin and other transport proteins

Answer 6

Beta globulins

Question 7

Immunoglobulins

Answer 7

Gamma globulins

Question 8

Lifespan of platelets

Answer 8

7-10 days

Question 9

Processing of forming blood cells in the bone marrow

Answer 9

Haemopoesis

Question 10

Site of blood cell formation less than 2months AOG

Answer 10

Yolk sac (AORTIC GONAD MESONEPHROS)

Question 11

Site of blood cell formation from 3rd month AOG to birth?

Answer 11

LIVER and spleen

Question 12

Only source of blood POSTnatally; begins at 4th month AOG

Answer 12

Bone marrow

Question 13

All bone marrow are active

Answer 13

Birth to Puberty

Question 14

Only bone marrow of vertebrae, ribs, sternum, skull, pelvis, proximal epiphyseal region of humerus active

Answer 14

Age 20

Question 15

Post-embryonic extramedullary hematopoiesis in full-term infant

Answer 15

Always abnormal

Question 16

Carbon dioxide attached to Hgb

Answer 16

Carbamino hemoglobin

Question 17

Carbon monoxide attached to Hgb

Answer 17

Carboxyhemoglobin

Question 18

Oxygen attached to Hgb

Answer 18

Oxyhemoglobin

Question 19

Size of. RBC

Answer 19

Length: 8um
Width: 2um

Question 20

Hemoglobin values
Male:
Female:

Answer 20

Male: 14-18g/dL
Female: 12-18g/dL

Question 21

Normal Hematocrit Values:

Answer 21

Male: 46 (40-54)
Female: 42 ( 37-47)

Question 22

How many O2 molecules can 1 hemoglobin molecule bind

Answer 22

4 oxygen molecules

Question 23

Hemoglobin A

Answer 23

2 alpha and 2 beta

Question 24

Hemoglobin F

Answer 24

2 alpha and 2 gamma

Question 25

Total iron in the body

Answer 25

4-5 grams

Question 26

Iron found in plasma

Answer 26

Transferrin

Question 27

Iron found in LIVER

Answer 27

Ferritin

Question 28

Storage form of iron found outside the liver

Answer 28

Hemosiderin

Question 29

Enzyme responsible in synthesis of Hemoglobin

Answer 29

Amino Levolinic Acid Synthase (ALA synthase)

Question 30

Hormone stimulating RBC production

Answer 30

Erythropoietin

Question 31

Main stimulus for EPO peoduction

Answer 31

Hypoxia

Question 32

Effect of EPO will after this many days

Answer 32

5 days

Question 33

Last RBC stage with a nucleus

Answer 33

Orthochromatic erythroblast

Question 34

RBC stage released to the blood

Answer 34

Reticulocyte

Question 35

Time to convert reticulocytes to mature RBCs

Answer 35

1-2 days

Question 36

Characteristics of mature RBC’s

Answer 36

No nucleus
No mitochondria
No ER

Question 37

Lifespan of adult RBC’s

Answer 37

120 days

Question 38

Lifespan of fetal RBC’s

Answer 38

90 days

Question 39

Intravascular destruction of old or damaged RBCs occurs here

Answer 39

Spleen

Question 40

Extravascular destruction of RBCs is due to

Answer 40

Macrophages

Question 41

Fate of Heme in destroyed RBC

Answer 41

Bilirubin

Question 42

Nutrient essential for DNA synthesis

Answer 42

Vitamin B12

Folic acid

Question 43

Megaloblastic anemia + Neural deficits

Answer 43

Vitamin B12 deficiency

Question 44

Megaloblastic anemia + Neural tube disorders

Answer 44

Folic acid deficiency

Question 45

Needed to absorb Vitamin B12

Answer 45

Intrinsic Factor in Terminal Ileum

Question 46

Source of Vitamin B12

Answer 46

Meats

Question 47

Source of Folic acid

Answer 47

Leafy vegetables