Hematology/Oncology Flashcards

0
Q

What is the most common inherited bleeding disorder?

A

vWF deficiency

Symptoms worsened with ASA use

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1
Q

What are the contents of cryoprecipitate?

A

Factor VIII, XIII, vWF, fibrinogen, fibronectin

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2
Q

Ristocetin cofactor assay is used to measure what?

A

Measures ability of vWF to agglutinate

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3
Q

What is the most common hereditary thrombotic disease?

A

Factor V leiden

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4
Q

What are the 3 causes of microangiopathic hemolytic anemia?

A

DIC,HUS, TTP

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5
Q

What is the DOC for TTP ?

A

Corticosteroid

Platelet transfusion is contraindicated

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6
Q

What is the most common immunologic disorder in women of child bearing age?

A

IT

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7
Q

Aplastic crisis is seen in which organism?

A

Parvovirus B19

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8
Q

Sickle cell osteomyelitis is associated with which organism?

A

Salmonella

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9
Q

An example of an iron chelator?

A

Deferoxamine

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10
Q

What are the 3 forms of inherited porphyria?

A
Porphyria	Acute intermittent porphyria (AD)
Porphyria cutana tarda
Erythropoietic prophyria (AR)
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11
Q

What are 4 oncologic emergencies?

A

Hypercalcemia
Spinal cord compression
Superior vena cava syndrome
Leukostasis (blasts occluding microcirculation)

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12
Q

Which type of AML has the best prognosis?

A

Acute promyelocytic leukemia (APL)

Responsive to all-trans-retinoic acid
AML type (FAB) M3
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13
Q

ALL is most commonly seen in which age group?

A

Children

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14
Q

What is the most common type of leukemia?

A

CLL

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15
Q

What is the most common hematopoietic neoplasm?

A

Non-Hodgkin’s lymphoma

16
Q

Translocation in Hodgkin’s lymphoma?

A

t(14,18)

17
Q

Pel Ebstein fever is found in?

A

Hodgkin’s lymphoma

1-2 weeks high fever alternating with 1-2 week afebrile

18
Q

M protein is associated with which protein?

A

Multiple myeloma

CLL, lymphoma, Waldenstrom’s macroglobulinemia, amyloidosis

19
Q

Waldenstrom’s macroglobulinemia reveals which elevated immunoglobulin?

A

Elevated IgM levels