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Pharmacology drugs of the pathologies > Hematology > Flashcards

Hematology Flashcards

1
Q

Treatment for iron deficiency anaemia?

A

Ferrous sulfate and ferrous fumarate tablets

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2
Q

Ferrous sulfate and ferrous fumarate tablet side effects (think main and others)?

A

Black stool

Constipation, diarrhoea, nausea, GI upset

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3
Q

Anti-folate drug example - can cause folate deficient anemia?

A

Methotrexate

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4
Q

Treatment for pernicious anaemia?

A

B12 supplementation

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5
Q

For pernicious anaemia giving folate instead of B12 causes…?

A

A fulminant neurological deficit

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6
Q

Haemolytic Anaemia drugs given x2?

A

Iron and folate supplements

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7
Q

Treatment for JAK2 gene mutation primary polycythaemia?

A

Bloodletting, aspirin

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8
Q

Haemolytic anaemia surgical treatment?

A

Splenectomy

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9
Q

Supportive treatment for sickle cell anaemia?

A

Opiates, antibiotics, fluids, folic acid

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10
Q

Purpose of iron chelatin in thalassaemia treatment?

A

Will reduce iron overload

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11
Q

Primary polycythemia treatment?

A

For rubra vera (JAK2) aspirin or bloodletting

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12
Q

Secondary polycythemia treatment?

A

Treat underlying cause

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13
Q

Treatment for acute leukemia x3?

A

Chemotherapy
BMT
Supportive

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14
Q

Supportive treatment for acute leukaemia? x3

A

Blood products
Prophylactic abx
Allopurional

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15
Q

What is an additional Tx for AMPL?

A

ATRA

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16
Q

Philadelphia chromosome in CML?

A

Translocation between 9 and 22 chromosome long arms resulting in tyrosinase kinase activity and an ONCOGENE resulting.

17
Q

CML treatment?

A

Imatinab if Ph positive
Stem cell transplantation
Chemo

18
Q

What drugs for CLL?

A

Fludarabine and rituximab +/- cyclophosphamide

19
Q

CLL treatment? x3

A

Drugs
Steroids - autoimmune haemolysis
Chemo/radio for splenectomy or lymphadenopathy

20
Q

Tx for DVT? x3

A

NOACs
Heparin LMW
Warfarin

Pharmacology drugs of the pathologies (4 decks)

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