Hematology Flashcards
Treatment for iron deficiency anaemia?
Ferrous sulfate and ferrous fumarate tablets
Ferrous sulfate and ferrous fumarate tablet side effects (think main and others)?
Black stool
Constipation, diarrhoea, nausea, GI upset
Anti-folate drug example - can cause folate deficient anemia?
Methotrexate
Treatment for pernicious anaemia?
B12 supplementation
For pernicious anaemia giving folate instead of B12 causes…?
A fulminant neurological deficit
Haemolytic Anaemia drugs given x2?
Iron and folate supplements
Treatment for JAK2 gene mutation primary polycythaemia?
Bloodletting, aspirin
Haemolytic anaemia surgical treatment?
Splenectomy
Supportive treatment for sickle cell anaemia?
Opiates, antibiotics, fluids, folic acid
Purpose of iron chelatin in thalassaemia treatment?
Will reduce iron overload
Primary polycythemia treatment?
For rubra vera (JAK2) aspirin or bloodletting
Secondary polycythemia treatment?
Treat underlying cause
Treatment for acute leukemia x3?
Chemotherapy
BMT
Supportive
Supportive treatment for acute leukaemia? x3
Blood products
Prophylactic abx
Allopurional
What is an additional Tx for AMPL?
ATRA
Philadelphia chromosome in CML?
Translocation between 9 and 22 chromosome long arms resulting in tyrosinase kinase activity and an ONCOGENE resulting.
CML treatment?
Imatinab if Ph positive
Stem cell transplantation
Chemo
What drugs for CLL?
Fludarabine and rituximab +/- cyclophosphamide
CLL treatment? x3
Drugs
Steroids - autoimmune haemolysis
Chemo/radio for splenectomy or lymphadenopathy
Tx for DVT? x3
NOACs
Heparin LMW
Warfarin
